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Cytotoxic constituents of the stem bark of Neolitsea acuminatissima.
Three new eudesmanolide sesquiterpenes, neolitacumone A-C (1-3), and one new benzylisoquinoline alkaloid, neolitacumonine (5), along with 27 known compounds were isolated from the stem bark ofExpand
Plant-derived triterpenoids and analogues as antitumor and anti-HIV agents.
Covering: January 2006 to December 2008 This article reviews the antitumor and anti-HIV activities of naturally occurring triterpenoids, including the lupane, ursane, oleanane, lanostane,Expand
Antiplatelet activity of N-methoxycarbonyl aporphines from Rollinia mucosa.
Bioassay-directed fractionation of the stems of Rollinia mucosa led to the isolation of new N-methoxycarbonyl aporphine alkaloids, romucosine A (1), romucosine B (2), romucosine C (3), and romucosineExpand
New alkaloids from Annona purpurea.
Three new alkaloids, promucosine (1), romucosine F (2), and romucosine G (3), along with 28 known compounds, were isolated from the MeOH extract of stems of Annona purpurea. The structures of 1-3Expand
A New Phenanthrene Alkaloid, Romucosine I, form Rollinia mucosa Baill
Bioactivity-directed fractionation led to the isolation of a new N-(methoxycarbonyl) phenanthrene alkaloid, romucosine I (1), along with three known N-(methoxycarbonyl) alkaloids, romucosine C (2),Expand
Suppression of respiratory burst in human neutrophils by new synthetic pyrrolo-benzylisoquinolines.
Reactive oxygen species produced by neutrophils contribute to the pathogenesis of inflammatory diseases. In this study, the inhibition of superoxide anion (O2*-) generation in human neutrophils byExpand
A new propentdyopent derivative, rollipyrrole, from Rollinia mucosa Baill.
Abstract Rollipyrrole 1 , a novel pyrromethenone derivative was isolated from the leaves of Rollinia mucosa in the continuing research into Formosan annonaceous plants. This type of compound wasExpand
Antiplatelet activity of synthetic pyrrolo-benzylisoquinolines.
Pyrrolo-benzylisoquinolines were prepared as target compounds and their antiplatelet aggregation activity, adreno-receptor affinity, and cytotoxicity were screened. Compounds 1d-9d showed specificExpand
Antiplatelet effects of KW-7, a new inhibitor of cyclic nucleotide phosphodiesterases.
The antiplatelet effect of a new synthetic compound, 8,9-dimethoxyl-1-(4-methoxy-phenyl)-5,6-dihydro-pyrrolo[2,1-a]isoquinoline-2,3-dione (KW-7), was determined in rabbit platelets. KW-7Expand