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The Role of Neuroimmunomodulation in Alzheimer's Disease
- R. Maccioni, L. Rojo, J. Fernández, R. Kuljiš
- Biology, Medicine
- Annals of the New York Academy of Sciences
- 1 February 2009
The idea that alterations in the brain immunomodulation are critical for Alzheimer's disease (AD) pathogenesis provides the most integrative view on this cognitive disorder, considering that… Expand
Exercise-Induced Cognitive Plasticity, Implications for Mild Cognitive Impairment and Alzheimer’s Disease
Lifestyle factors such as intellectual stimulation, cognitive and social engagement, nutrition, and various types of exercise appear to reduce the risk for common age-associated disorders such as… Expand
Beta-endorphin regulation of luteinizing hormone-releasing hormone release at the median eminence in ewes: immunocytochemical and physiological evidence.
Beta-endorphin (beta-END) is an inhibitory factor in the neuroendocrine control of luteinizing hormone (LH) release and thus, presumably also of hypophysiotropic luteinizing hormone-releasing hormone… Expand
Dementia, diabetes, Alzheimer's disease, and insulin resistance in the brain: progress, dilemmas, new opportunities, and a hypothesis to tackle intersecting epidemics.
Dementia is an increasingly prevalent condition that intersects worldwide with the epidemic of type 2 diabetes mellitus (DM2). It would seem logical to expect that the occurrence of DM2 increases the… Expand
Hypercolumns in primate visual cortex can develop in the absence of cues from photoreceptors.
The visual cortex in primates consists of an array of anatomically and chemically identifiable cellular modules (hypercolumns) with distinct physiological properties. For example, layers II/III in… Expand
Lewy bodies in tyrosine hydroxylase-synthesizing neurons of the human cerebral cortex
A population of neurons situated in the human cerebral neocortex contains mRNA coding for tyrosine hydroxylase, the key enzyme for catecholamine biosynthesis. Phosphorylated neurofilament-containing… Expand
Multiple types of nitrogen monoxide synthase-/NADPH diaphorase-containing neurons in the human cerebral neocortex
Nitrogen monoxide (NO) synthase (NOS)-containing neurons (NOSN) were identified by means of reduced nicotinamide adenine dinucleotide phosphate (NADPH) diaphorase histochemistry in nine areas of the… Expand
Lesions in the Pulvinar in Patients with Alzheimer's Disease
- R. Kuljiš
- Psychology, Medicine
- Journal of neuropathology and experimental…
- 1 March 1994
The pulvinar nucleus of the thalamus has been implicated in visual attention and in the control of eye movements, and may also help mediate attention-dependent tasks in the auditory and somatosensory… Expand
Identification of Fc gamma RI, II and III on normal human brain ramified microglia and on microglia in senile plaques in Alzheimer's disease.
Using monoclonal antibodies to the three known human leukocyte IgG receptors, Fc gamma R, we examined the expression of Fc gamma R in normal brains and in Alzheimer's disease. We found Fc gamma RI,… Expand
Bridging psychiatry and neurology through social neuroscience
- A. Ibáñez, R. Kuljiš, Diana Matallana, F. Manes
- Psychology, Medicine
- World psychiatry : official journal of the World…
- 1 June 2014
Social neuroscience launched a novel multilevel (neural, hormonal, molecular and genetic) explanation of social cognition in psychiatry. In particular, the use of different levels of scientific… Expand