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A risk-based strategy improves prostate-specific antigen-driven detection of prostate cancer.
BACKGROUND Screening for prostate cancer (PC) is controversial due to uncertainties about its efficiency. OBJECTIVE We aimed to develop strategies to reduce the number of unnecessary biopsies whileExpand
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Prostate cancer detection at low prostate specific antigen.
PURPOSE At low prostate specific antigen (PSA) the indication for prostate biopsy is usually an abnormal digital rectal examination. We evaluate the diagnostic value of PSA, digital rectalExpand
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Identification of Genetic Markers for Prostatic Cancer Progression
Despite the high incidence of prostate cancer, only limited data are available on genes or chromosomes specifically involved in its initiation and progression. We have applied comparative genomicExpand
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Evaluation of the digital rectal examination as a screening test for prostate cancer. Rotterdam section of the European Randomized Study of Screening for Prostate Cancer.
BACKGROUND The utility of digital rectal examination (DRE) as a screening test for early detection of prostate cancer has not been established. Therefore, we evaluated the usefulness of DRE as aExpand
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Computer-controlled wheelchair ergometer
A new wheelchair ergometer has been designed in which a combination of realistic simulation of wheelchair propulsion—with adjustable parameters for rolling resistance, air drag, wind speed andExpand
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Large‐scale randomized prostate cancer screening trials: Program performances in the European randomized screening for prostate cancer trial and the prostate, lung, colorectal and ovary cancer trial
Two large‐scale randomized screening trials, the Prostate, Lung, Colorectal and Ovary (PLCO) cancer trial in the USA and the European Randomized Screening for Prostate Cancer (ERSPC) trial in EuropeExpand
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Evaluation of the Digital Rectal Examination as a Screening Test for Prostate Cancer
Background: The utility of digital rectal examination (DRE) as a screening test for early detection of prostate cancer has not been established. Therefore, we evaluated the usefulness of DRE as aExpand
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Complications of transrectal ultrasound-guided systematic sextant biopsies of the prostate: evaluation of complication rates and risk factors within a population-based screening program.
OBJECTIVES Screening for prostate cancer to reduce the mortality and morbidity from this disease has become an important issue in recent years. Of all procedures used to diagnose prostate cancer,Expand
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Histopathological prostate cancer characteristics at radical prostatectomy after population based screening.
PURPOSE Although early detection of prostate cancer by prostate specific antigen based screening results in a shift towards more clinically organ confined tumors, changes in prostate cancerExpand
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Screening for prostate cancer: results of the Rotterdam section of the European randomized study of screening for prostate cancer.
BACKGROUND Evidence from randomized trials on the effects of screening for prostate cancer (PCa) on disease-specific mortality accumulates slowly with increasing follow-up. OBJECTIVE To assess dataExpand
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