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Combination of Pentamidine and Trimethoprim-Sulfamethoxazole in the Therapy of Pneumocystis carinii Pneumonia in Rats
Combined therapy is no more effective than trimethoprim-sulfamethoxazole alone in the treatment of P. carinii pneumonia, and the interaction of these two agents in the steroid-conditioned rat model of pneumocystosis is studied.
Listeria cerebritis. Relapse of infection in renal transplant patients.
High-dose penicillin or ampicillin therapy for four to six weeks is recommended for Listeriainfections in this select group of patients and a relapse rate of 35% is reported in transplant patients withListeriameningitis and/or bacteremia who are treated for less than three weeks.
Gas gangrene: review of 34 cases.
High morbidity and mortality continue to result from gas gangrene, despite the use of aggressive modes of therapy, and presence of normal or depressed white blood cell counts, decreased platelet counts, and abnormal renal or liver functions all denoted a poor prognosis.
Comparative Activity of Tobramycin, Amikacin, and Gentamicin Alone and with Carbenicillin Against Pseudomonas aeruginosa
The effect of gentamicin against 130 clinical isolates of Pseudomonas aeruginosa was compared with that of two investigational aminoglycoside antibiotics, tobramycin and amikacin, and the combination of carbenicillin and amkacin enhanced inhibition against all but two of the isolates.
Bacteremia associated with angiography.
Positive bacterial cultures were obtained from catheters and guide wires or blood, or both, during 23 of 100 angiographic procedures, and postprocedure temperature elevations were not proved to be related to catheter-induced infection.
Antimicrobial vs placebo prophylaxis in noncardiac thoracic surgery.
A prospective, double-blind evaluation of the efficacy and safety of prophylactic cephalosporins was done in 57 patients undergoing noncardiac thoracic surgery, and no differences were noted in WBC counts, fever, duration of hospitalization, hypersensitivity reactions, or abnormal liver functions.
Listeriosis--problems and therapeutic options.
  • R. Kluge
  • Medicine
    The Journal of antimicrobial chemotherapy
  • 1 June 1990
Rocky Mountain spotted fever and jaundice. Two consecutive cases acquired in Florida and a review of the literature on this complication.
In two patients with illnesses resembling leptospirosis, jaundice appeared on the sixth and ninth day of illness, and peak bilirubin levels were between 7 and 9 mg/100 ml.
Fatal Neisseria (Branhamella) catarrhalis pneumonia in an immunodeficient host.
A 64-year-old man with far-advanced IgA multiple myeloma presented with fulminant and rapidly fatal bronchopneumonia with the presence of numerous gram-negative diplococci in the alveolar spaces.