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VIP21, a 21-kD membrane protein is an integral component of trans-Golgi- network-derived transport vesicles
It is proposed that VIP21, a cDNA encoding one protein of this complex, VIP21 (Vesicular Integral-membrane Protein of 21 kD), is a component of the molecular machinery of vesicular transport. Expand
Involvement of the Transmembrane Protein p23 in Biosynthetic Protein Transport
The localization and characterization of BHKp23 are reported, and it is proposed that p23 contributes to membrane structure, and is necessary for efficient segregation and transport. Expand
Prepeptide sequence of epidermin, a ribosomally synthesized antibiotic with four sulphide-rings
It is proposed that the N-terminus (–30 to –1) plays a cooperative role during modification reactions and prevents toxicity of the mature epidermin to the producing strain before the antibiotic is cleaved off and secreted. Expand
Specific release of membrane-bound annexin II and cortical cytoskeletal elements by sequestration of membrane cholesterol.
The biochemical and immunological observations indicate that the cortical cytoskeletal proteins alpha-actinin, ezrin and moesin, and membrane-associated actin are part of a complex containing annexin II and that stability of the complex is sensitive to cholesterol sequestering agents. Expand
Structure of the anchor-domain of myristoylated and non-myristoylated HIV-1 Nef protein.
Negative factor (Nef) is a regulatory myristoylated protein of human immunodeficiency virus (HIV) that has a two-domain structure consisting of an anchor domain and a core domain separated by aExpand
VIP36, a novel component of glycolipid rafts and exocytic carrier vesicles in epithelial cells.
It is speculated that VIP36 binds to sugar residues of glycosphingolipids and/or glycosylphosphatidyl‐inositol anchors and might provide a link between the extracellular/luminal face of glycolipid rafts and the cytoplasmic protein segregation machinery. Expand
A Family of Neuropeptides That Inhibit Juvenile Hormone Biosynthesis in the Cricket, Gryllus bimaculatus(*)
Four nonapeptides that inhibit juvenile hormone synthesis have been isolated by four high performance liquid chromatographic steps from extracts of the brain of the field cricket, GryllusExpand
Interaction of glutamic-acid-rich proteins with the cGMP signalling pathway in rod photoreceptors
This work identifies GARPs as multivalent proteins that interact with the keyplayers of cGMP signalling, phosphodiesterase and guanylate cyclase, and with a retina-specific ATP-binding cassette transporter (ABCR), through four, short, repetitive sequences. Expand
Gallidermin: a new lanthionine-containing polypeptide antibiotic.
The isolation procedures for gallidermin included adsorption directly from the culture broth, ion-exchange chromatography of the amphiphilic and basic polypeptide followed by desalting, and final purification by reversed-phase HPLC, which involved mainly a combination of automated gas-phase sequencing, thermospray liquid chromatography/mass spectrometry and fast-atom-bombardment mass spectromaetry. Expand
Existence of distinct tyrosylprotein sulfotransferase genes: molecular characterization of tyrosylprotein sulfotransferase-2.
An approach to identify the TPST protein, referred to as MSC (modification after substrate crosslinking) labeling, which is based on the crossl linking of a substrate peptide to TPST followed by intramolecular [35S]sulfate transfer from the cosubstrate 3-phosphoadenosine 5'-phosphosulfate (PAPS). Expand