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Synthesis and structure revision of tyroscherin, and bioactivities of its stereoisomers against IGF-1-dependent tumor cells
Synthesis of the proposed structure of tyroscherin, a growth inhibitor of IGF-1-dependent cancer cells, was succeeded by one-pot Julia coupling. However, spectral data of the synthetic compound wereExpand
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Concise Syntheses and Biological Activities of Ganomycin I and Fornicin A
The first enantioselective syntheses of ganomycin I, a meroterpenoid isolated from the Vietnamese mushroom Ganoderma colossum, and the related meroterpenoid fornicin A were accomplished. OurExpand
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Synthesis and structure revision of tyroscherin, a growth inhibitor of IGF-1-dependent tumor cells
Synthesis of the proposed structure of tyroscherin, a growth inhibitor of IGF-1-dependent cancer cells, was succeeded by one-pot Julia coupling. However, spectral data of the synthetic compound wereExpand
  • 12
Stereoselective synthesis of Sch 642305, an inhibitor of bacterial DNA primase
Sch 642305 is a fungal nonanolide, which inhibits bacterial DNA primase and HIV-1 Tat transactivation. The enantioselective synthesis of Sch 642305 was succeeded starting from useful chiral buildingExpand
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Synthesis of two osteoclast-forming suppressors, demethylincisterol A3 and chaxine A
Abstract The synthesis of two potent osteoclast-forming suppressing agents isolated from the Chinese mushroom Agrocybe chaxingu , demethylincisterol A 3 and chaxine A, was accomplished usingExpand
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Total synthesis of epicoccamides A and D via olefin cross-metathesis
Epicoccamides A and D were synthesized through a route that utilizes fragment coupling via olefin cross-metathesis as a key step. The right-hand segment of the epicoccamides was synthesized by aExpand
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Stereocontrolled total synthesis of (±)-3β-hydroxy-9β-pimara-7,15-diene, a putative biosynthetic intermediate of momilactones
Abstract The total synthesis of (±)-3β-hydroxy-9β-pimara-7,15-diene ( 1 ), a putative biosynthetic intermediate of the momilactones, was accomplished stereoselectively. Our methodology for theExpand
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Total synthesis of virgineone aglycone and stereochemical assignment of natural virgineone
Abstract The first total synthesis of virgineone aglycone has been achieved employing the tandem O -acylation–migration reaction and the olefin cross-metathesis as key steps for fragment couplings.Expand
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Synthesis of the core framework of the proposed structure of sargafuran
Synthesis of 2-homoprenyl-1-methyl-3-(5-methylfuran-2-yl)cyclopenta-2,4-dien-1-ol, the core framework of the proposed structure of the brown alga derived natural product sargafuran, was achieved inExpand
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