• Publications
  • Influence
Symbiotic Streptomycetes provide antibiotic combination prophylaxis for wasp offspring.
TLDR
The complementary action of all symbiont-produced antibiotics confers a potent antimicrobial defense for the wasp larvae that parallels the 'combination prophylaxis' known from human medicine. Expand
Phenalenone-type phytoalexins mediate resistance of banana plants (Musa spp.) to the burrowing nematode Radopholus similis
TLDR
It is demonstrated that secondary metabolites (phenylphenalenones) of Musa are the reason for differences in cultivar resistance, and detected the phenyl phenalenone anigorufone in greater concentrations in lesions in roots of a nematode-resistant cultivar than in those of a susceptible one. Expand
Computing fragmentation trees from tandem mass spectrometry data.
TLDR
This work presents a method for interpreting the CID spectra of the organic compound's protonated ions by computing fragmentation trees that establish not only the molecular formula of the compound and all fragment ions but also the dependencies between fragment ions. Expand
Conservation and clade-specific diversification of pathogen-inducible tryptophan and indole glucosinolate metabolism in Arabidopsis thaliana relatives.
TLDR
It is concluded that pathogen-inducible IG metabolism in the Brassicaceae is evolutionarily ancient, while other tryptophan-derived branch pathways represent relatively recent manifestations of a plant-pathogen arms race. Expand
The biosynthetic origin of oxygen functions in phenylphenalenones of Anigozanthos preissii inferred from NMR- and HRMS-based isotopologue analysis.
TLDR
The isotopologue patterns inferred from NMR and HRESIMS analyses indicated that the hydroxyl group at C-2 of 9-phenylphenalenones had been introduced on the stage of a linear diarylheptanoid. Expand
Biosynthesis of Nudicaulins: A 13CO2‐Pulse/Chase Labeling Study with Papaver nudicaule
TLDR
The deconvolution of the labeling profiles indicated that the nudicaulin scaffold is assembled from products or intermediates of indole metabolism, the phenylpropanoid pathway, and the polyketide biosynthesis. Expand
Biosynthesis of tetraoxygenated phenylphenalenones in Wachendorfia thyrsiflora.
TLDR
Results suggest that the oxygen atoms decorating the phenalenone tricycle are introduced at different biosynthetic stages in the sequence O-1→O-2→ O-5. Expand
Computing Fragmentation Trees from Tandem Mass
The structural elucidation of organic compounds in complex biofluids and tissues remains a significant analytical challenge. For mass spectrometry, the manual interpretation of collision-inducedExpand