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Coenzyme Q10: Absorption, tissue uptake, metabolism and pharmacokinetics
Available data on the absorption, metabolism and pharmacokinetics of coenzyme Q10 (CoQ10) are reviewed in this paper. CoQ10 has a fundamental role in cellular bioenergetics. CoQ10 is also an… Expand
Plasma coenzyme Q10 response to oral ingestion of coenzyme Q10 formulations.
Plasma coenzyme Q10 (CoQ10) response to oral ingestion of various CoQ10 formulations was examined. Both total plasma CoQ10 and net increase over baseline CoQ10 concentrations show a gradual increase… Expand
Dietary coenzyme Q10 and vitamin E alter the status of these compounds in rat tissues and mitochondria.
- W. Ibrahim, H. Bhagavan, R. K. Chopra, C. Chow
- Biology, Medicine
- The Journal of nutrition
- 1 September 2000
Vitamin E (VE) and coenzyme Q (CQ) are essential for maintaining functions and integrity of mitochondria, and high concentrations of these compounds are found in their inner membranes. This study was… Expand
Relative bioavailability of coenzyme Q10 formulations in human subjects.
- R. K. Chopra, R. Goldman, S. Sinatra, H. Bhagavan
- International journal for vitamin and nutrition…
The relative bioavailability of typical commercially available forms of coenzyme Q10 (CoQ10) was compared with that of Q-Gel, a new solubilized form of CoQ10, in human subjects in two separate… Expand
Randomized, Double-Blind Placebo-Controlled Trial of Coenzyme Q10 in Patients with Acute Myocardial Infarction
- R. Singh, G. Wander, +6 authors R. K. Chopra
- Cardiovascular Drugs and Therapy
- 1 September 1998
The effects of oral treatment with coenzyme Q10 (120 mg/d) were compared for 28 days in 73 (intervention group A) and 71 (placebo group B) patients with acute myocardial infarction (AMI). After… Expand
Potential role of ubiquinone (coenzyme Q10) in pediatric cardiomyopathy.
Pediatric cardiomyopathy (PCM) represents a group of rare and heterogeneous disorders that often results in death. While there is a large body of literature on adult cardiomyopathy, all of the… Expand
The Effect of Exercise and Nutritional Supplementation on Proinflammatory Cytokine Expression in Young Racehorses During Training
- D. Horohov, S. Sinatra, R. K. Chopra, Stanley N. Jankowitz, A. Betancourt, R. Bloomer
- 1 December 2012
The inflammatory response to vigorous exercise ranges from the mild symptoms of delayed-onset muscle soreness to debilitating injuries affecting soft tissue, joint, and bone. Although there is a… Expand
Coenzyme Q 10 and Neoplasia: Overview of Experimental and Clinical Evidence*
36.1 The Integration of Cancer, Immune System, Aging, and Coenzyme Q .............................599 36.1.1 The View from Afar… Expand
Assessment of coenzyme Q10 absorption using an in vitro digestion-Caco-2 cell model.
- H. Bhagavan, R. K. Chopra, N. Craft, C. Chitchumroonchokchai, M. Failla
- Chemistry, Medicine
- International journal of pharmaceutics
- 21 March 2007
The feasibility of using a coupled in vitro digestion-Caco-2 cell uptake as a model for examining the digestive stability and absorption of coenzyme Q10 (CoQ10) from a variety of commercially… Expand
Immunoprobes for polychlorinated dibenzodioxins: Synthesis of immunogen and characterization of antibodies
We have synthesized a novel dioxin immunogen, 2‐adipamide‐7, 8‐dichlorodibenzodioxin‐BSA, with a view to generating antibodies suitable for use in an immunoaffinity column. The specificity of… Expand