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Interactions with aromatic rings in chemical and biological recognition.
This review focuses mainly on examples with biological relevance since one of its aims it to enhance the knowledge of molecular recognition forces that is essential for drug development.
Polycaps: reversibly formed polymeric capsules.
These assemblies are assemblies consisting of polymeric capsules, "polycaps," formed from two calix[4]arene tetraureas covalently connected at their lower rims, characterized by 1H NMR spectroscopy through encapsulation of guest species, reversible polymerization, and the formation of sharply defined hybrid capsules.
Investigating Molecular Recognition by Mass Spectrometry: Characterization of Calixarene-Based Self-Assembling Capsule Hosts with Charged Guests
Capsules derived from the reversible assembly of calixarene tetraureas have been characterized by electrospray ionization mass spectrometry. Ion labeling was achieved through the encapsulation of
Transfer of Chiral Information through Molecular Assembly
Calix[4]arenes substituted with ureas on their upper, wider rims form dimers in solution held together by a seam of 16 hydrogen bonds. The resulting molecular capsules have interiors capable of
Synthesis and Self-Assembly of Functionalized Donor−σ−Acceptor Molecules
3,5,7-Tris(arylmethyl)-1-aza-adamantanetrione donor−σ−acceptor compounds have been synthesized in four steps. Computational and 1H NMR analyses rationalize the solubility, gelation, and
Detection and Mechanistic Studies of Multicomponent Assembly by Fluorescence Resonance Energy Transfer
The kinetics and thermodynamics of multicomponent assembly in organic solution are investigated using fluorescence resonance energy transfer (FRET). Calix[4]arenes functionalized with ureas on their
Synthesis, photophysical behavior, and electronic structure of push-pull purines.
"Push-pull" purines have been synthesized by the introduction of electron-accepting functional groups (A = CN, CO(2)Me, and CONHR) to the heterocyclic C(8) position to complement typical