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Dandruff Is Associated with Disequilibrium in the Proportion of the Major Bacterial and Fungal Populations Colonizing the Scalp
TLDR
It is suggested for the first time using molecular methods, that dandruff is linked to the balance between bacteria and fungi of the host scalp surface. Expand
Sensitive skin: an epidemiological study
Background There is a growing awareness that some individuals exhibit heightened skin sensitivity, particularly on the face, and have a high incidence of adverse reactions to cosmetics and toiletries.
Endocannabinoids Stimulate Human Melanogenesis via Type-1 Cannabinoid Receptor*
TLDR
It is shown that at higher concentrations AEA induces normal human epidermal melanocyte apoptosis through a TRPV1-mediated pathway that increases DNA fragmentation and p53 expression, and at lower concentrations, AEA and other CB1-binding endocannabinoids dose-dependently stimulate melanin synthesis and enhance tyrosinase gene expression and activity. Expand
Body Site Is a More Determinant Factor than Human Population Diversity in the Healthy Skin Microbiome
TLDR
Skin swabbing is confirmed as a useful method for sampling different areas of the skin because DNA concentrations and number of sequences obtained across subject libraries were similar and skin location was the main factor determining the composition of bacterial communities. Expand
Characterization of the major bacterial–fungal populations colonizing dandruff scalps in Shanghai, China, shows microbial disequilibrium
TLDR
The data obtained from the Chinese populations were highly similar to those obtained in France, confirming that dandruff scalps are associated with a higher incidence of Malassezia restricta and Staphylococcal sp. Expand
Detection thresholds of capsaicin: a new test to assess facial skin neurosensitivity.
TLDR
This new test of skin neurosensitivity is easy, quick, and truly painless and appears to be a promising tool for the cosmetic diagnosis of sensitive skin. Expand
Exploration of scalp surface lipids reveals squalene peroxide as a potential actor in dandruff condition
TLDR
The results indicated that Malassezia could be a major source of squalene peroxidation on the scalp, and increased SQOOH could be considered as a new etiological dandruff factor via its ability to impair scalp barrier function. Expand
Ethnic variations in self‐perceived sensitive skin: epidemiological survey
TLDR
Differences in skin sensitivity between ethnic groups concerned mostly factors of skin reactivity and, to a lesser extent, its symptomatology but, taken together, note the similarities in comparing how women of varying ethnic backgrounds perceive the sensitive skin condition. Expand
Chemical Organization of the Cell Wall Polysaccharide Core of Malassezia restricta
TLDR
The composition of cell wall polysaccharides of M. restricta is unique in the fungal kingdom, showing that they play an essential role in the organization and rigidity of the M. restrictiona cell wall. Expand
Anandamide Suppresses Proinflammatory T Cell Responses In Vitro through Type-1 Cannabinoid Receptor–Mediated mTOR Inhibition in Human Keratinocytes
TLDR
Findings demonstrate that AEA suppresses highly pathogenic T cell subsets through CB1-mediated mammalian target of rapamycin inhibition in human keratinocytes, and it can be speculated that the latter pathway might be beneficial to the physiological function of the skin, and can be targeted toward inflammation-related skin diseases. Expand
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