• Publications
  • Influence
Risk factors and mortality associated with calciphylaxis in end-stage renal disease.
TLDR
Female gender, hyperphosphatemia, high alkaline phosphatase, and low serum albumin are risk factors for calciphylaxis, which is associated with a very high mortality in end-stage renal disease. Expand
Mycophenolate mofetil prevents salt-sensitive hypertension resulting from angiotensin II exposure.
TLDR
SSHTN resulting from Ang II infusion is associated with infiltration and activation of immune cells that produce Ang II and mycophenolate mofetil treatment reduces these features and prevents the development of SSHTN. Expand
Role of immunocompetent cells in nonimmune renal diseases.
TLDR
This review focuses on the investigations that have shown accumulation of immunocompetent cells in experimental models of acute and chronic ischemia, protein overload, hypercholesterolemia, renal ablation, obstructive uropathy, polycystic kidney disease, diabetes, aging, murine hypertension, and nephrotoxicity. Expand
Reappraisal of the pathogenesis and consequences of hyperuricemia in hypertension, cardiovascular disease, and renal disease.
TLDR
This article suggests that hyperuricemia may be mediated by intrarenal ischemia with lactate generation and the inhibition of the secretion of urate by the anion-exchange transport system, and further studies are necessary to rule out a pathogenic role for uric acid in the development of renal disease and salt-dependent hypertension. Expand
Risk of death among chronic dialysis patients infected with hepatitis C virus.
TLDR
Hepatitis C virus infection increased the risk for death among chronic dialysis patients who were positive for the HCV antibody and HCV RNA compared with negative patients, and the measures used to prevent and treat HCV infection were assessed. Expand
Sex differences in uric acid and risk factors for coronary artery disease.
TLDR
Tissue factor expression on macrophages in coronary plaques in patients with unstable angina and the effects of angiotensin metabolites on the regulation of coagulation and fibrinolysis in cultured rat aortic endothelial cells. Expand
Unearthing uric acid: an ancient factor with recently found significance in renal and cardiovascular disease.
TLDR
Clinical studies are urgently needed to examine the possibility that uric acid may contribute to the development of hypertension, metabolic syndrome, and kidney disease in some patients. Expand
Mycophenolate mofetil prevents salt-sensitive hypertension resulting from nitric oxide synthesis inhibition.
TLDR
MHF treatment prevented the development of hypertension in response to a high-salt diet, and correlated with the ability of MMF to inhibit specific aspects of the renal injury, including theDevelopment of segmental glomerulosclerosis, the infiltration of T cells and ANG II-positive cells, and the thickening of afferent arterioles. Expand
Hepatitis C virus infection and membranoproliferative glomerulonephritis in Japan.
TLDR
The six patients with HCV-MPGN were similar to the four patients with idiopathic MPGN with respect to age, presence of nephrotic syndrome, and renal dysfunction, but had a higher incidence of liver dysfunction, cryoglobulinemia, rheumatoid factor, and hypocomplementemia. Expand
Chronic potassium depletion induces renal injury, salt sensitivity, and hypertension in young rats.
TLDR
Dietary potassium deficiency per se increases the BP in young rats and induces salt sensitivity that may involve at least two different pathogenic pathways: increased RAS activity and induction of tubulointerstitial injury. Expand
...
1
2
3
4
5
...