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Course of illness, hippocampal function, and hippocampal volume in major depression
Comparing hippocampal function, as assessed by performance on hippocampal-dependent recollection memory tests, and hippocampal volumes, as measured in a 1.5-T magnetic resonance imager, in depressed subjects experiencing a postpubertal onset of depression revealed a significant logarithmic association between illness duration and hippocampusal volume. Expand
Relationship between the five-factor model of personality and unipolar, bipolar and schizophrenic patients
The purpose of this study was to examine personality differences among three different Axis I disorders-recovered patients with unipolar depression (n = 62), euthymic patients with bipolar disorderExpand
A placebo-controlled comparison of lithium and triiodothyronine augmentation of tricyclic antidepressants in unipolar refractory depression.
This study suggests that both lithium and liothyronine may be considered as alternatives in augmenting antidepressant response in patients who do not respond to treatment with a tricyclic antidepressant. Expand
A review of psychosocial outcome in patients with bipolar disorder
Outcome in patients with bipolar disorder as assessed by interepisode level of functioning is reviewed, as until recently this dimension of outcome has been relatively under‐emphasized. Expand
Course of Illness, Hippocampal Function, and Hippocampal Volume in Major Depression
Studies have examined hippocampal function and volume in depressed subjects, but none have systematically compared never-treated first-episode patients with those who have had multiple episodes. WeExpand
A comparison of Tridimensional Personality Questionnaire dimensions in bipolar disorder and unipolar depression
It is suggested that high HA scores may be associated with a mood disorder diagnosis, whereas high NS scores may been associated with the BD subtype. Expand
Subsyndromal symptoms assessed in longitudinal, prospective follow-up of a cohort of patients with bipolar disorder.
Persistent subsyndromal symptoms in BD patients are associated with high rates of comorbidity that is important to recognize and treat in order to optimize mood and functioning. Expand
Anxious and non-anxious bipolar disorder.
Anxiety may have similar clinical relevance in BD as it does in unipolar patients and diagnosis of an anxiety disorder was related only to high anxiety and lower GAS scores. Expand
Triiodothyronine augmentation in the treatment of refractory depression. A meta-analysis.
Triiodothyronine augmentation may be an effective empirical method of increasing response rates and decreasing depression severity scores in a subgroup of patients with depression refractory to tricyclic antidepressant therapy, but the total number of patients randomized was small, and additional placebo-controlled data are required for a definitive verdict. Expand
Double-blind comparison of addition of a second mood stabilizer versus an antidepressant to an initial mood stabilizer for treatment of patients with bipolar depression.
Both treatments appeared to be effective; however, the addition of an antidepressant may have greater clinical utility in the treatment of bipolar depression. Expand