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Infections in 252 patients with common variable immunodeficiency.
BACKGROUND Common variable immunodeficiency is characterized by recurrent infections and defective immunoglobulin production. METHODS The DEFI French national study prospectively enrolled adultExpand
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Efficacy and safety of rituximab in common variable immunodeficiency‐associated immune cytopenias: a retrospective multicentre study on 33 patients
Patients with common variable immunodeficiency (CVID) are at high risk of developing immune thrombocytopenia (ITP) and/or autoimmune haemolytic anaemia (AHA). Given their underlying immunodeficiency,Expand
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Population pharmacokinetics of pyrimethamine and sulfadoxine in children with congenital toxoplasmosis.
AIMS To develop a population pharmacokinetic model for pyrimethamine (PYR) and sulfadoxine (SDX) in children with congenital toxoplasmosis. METHODS Children were treated with PYR (1.25 mg kg(-1))Expand
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Does the route of immunoglobin replacement therapy impact quality of life and satisfaction in patients with primary immunodeficiency? Insights from the French cohort “Visages”
BackgroundIgG replacement therapy (IgRT) in primary immunodeficiencies (PID) is a lifelong treatment which may be administered intravenously (IVIg) or subcutaneously (SCIg), at hospital or at home.Expand
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Antibody persistence following preexposure regimens of cell-culture rabies vaccines: 10-year follow-up and proposal for a new booster policy.
Subjects (n = 312) received either the human diploid cell rabies vaccine (HDCV) or the purified Vero cell rabies vaccine (PVRV) according to either two-injection (days 0 and 28) or three-injectionExpand
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Clinical results of enzyme replacement therapy in Fabry disease: a comprehensive review of literature
Enzyme replacement therapy (ERT) has been used to treat Fabry disease – a progressive lysosomal storage disorder – since 2001. Two preparations of the enzyme α‐galactosidase A are available inExpand
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Fatal Epstein-Barr Virus Primo Infection in a 25-Year-Old Man Treated with Azathioprine for Crohn's Disease
ABSTRACT We report a case of Epstein-Barr virus (EBV) primo infection with the development of successive infectious mononucleosis, hemophagocytic lymphohistiocytosis, and B-cell lymphoproliferativeExpand
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  • Open Access
Clinical Value of Specific Immunoglobulin E Detection by Enzyme-Linked Immunosorbent Assay in Cases of Acquired and Congenital Toxoplasmosis
ABSTRACT The clinical value of immunoenzymatic (enzyme-linked immunosorbent assay) detection of anti-Toxoplasma immunoglobulin E (IgE) was assessed by studying 2,036 sera from 792 subjects,Expand
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  • Open Access
Métastases mixtes cutanéo-osseuses révélatrices d’un carcinome hépatocellulaire
Resume Un homme de 55 ans etait hospitalise pour une tumefaction frontale gauche. Elle mesurait 6 centimetres de diametre. Elle etait indolore et battante a la palpation, avec un revetement cutaneExpand
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Efficacy of sildenafil on ischaemic digital ulcer healing in systemic sclerosis: the placebo-controlled SEDUCE study
Objective To assess the effect of sildenafil, a phosphodiesterase type 5 inhibitor, on digital ulcer (DU) healing in systemic sclerosis (SSc). Methods Randomised, placebo-controlled study in patientsExpand
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  • Open Access