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A Human Genome Diversity Cell Line Panel
A resource of 1064 cultured lymphoblastoid cell lines (LCLs) ([1][1]) from individuals in different world populations and corresponding milligram quantities of DNA is deposited at the Foundation Jean
The effective mutation rate at Y chromosome short tandem repeats, with application to human population-divergence time.
This value is used to estimate the times of the African Bantu expansion, the divergence of Polynesian populations (the Maoris, Cook Islanders, and Samoans), and the origin of Gypsy populations from Bulgaria.
The Levant versus the Horn of Africa: evidence for bidirectional corridors of human migrations.
The overall phylogeographic profile reveals several clinal patterns and genetic partitions that may indicate source, direction, and relative timing of different waves of dispersals and expansions involving these nine populations.
African origin of human-specific polymorphic Alu insertions.
These four polymorphic Alu insertions were shown to be absent from the genomes of a number of nonhuman primates, consistent with their arising as human genetic polymorphisms sometime after the human/African ape divergence.
Mutations in radial spoke head protein genes RSPH9 and RSPH4A cause primary ciliary dyskinesia with central-microtubular-pair abnormalities.
Investigation of the effect of knockdown or mutations of RSPH9 orthologs in zebrafish and Chlamydomonas indicate that radial spoke head proteins are important in maintaining normal movement in motile, "9+2"-structure cilia and flagella.
Characterization of ancestral and derived Y-chromosome haplotypes of New World native populations.
The ancestral founder haplotype, 0A, of the DYS199T lineage is identified and it is proposed that 0A is one of the most prevalent founder paternal lineages of New World aborigines.
A major Y-chromosome haplogroup R1b Holocene era founder effect in Central and Western Europe
Within the M412 dichotomy, the major S116 sub-clade shows a frequency peak in the upper Danube basin and Paris area with declining frequency toward Italy, Iberia, Southern France and British Isles, and more complex pre-Neolithic scenarios remain possible for the L23(xM412) components in Southeast Europe and elsewhere.
Genetic variation of recent Alu insertions in human populations
The results indicate that these polymorphic Alu insertions probably have an African origin and that there is a much smaller amount of genetic variation between European populations than that found between other populations groups.
Y-Chromosomal Diversity in Lebanon Is Structured by Recent Historical Events
The Islamic expansion from the Arabian Peninsula beginning in the seventh century CE introduced lineages typical of this area into those who subsequently became Lebanese Muslims, whereas the Crusader activity in the 11th–13th centuries CE introduced western European lineages into Lebanese Christians.
Y-chromosome diversity characterizes the Gulf of Oman
High-resolution Y-chromosome analysis of males from the United Arab Emirates, Qatar and Yemen revealed high diversity in their Y-haplogroup substructure possibly a result of gene flow along the coastal crescent-shaped corridor of the Gulf of Oman facilitating human dispersals.