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Poststernotomy mediastinitis: a review of conventional surgical treatments, vacuum-assisted closure therapy and presentation of the Lund University Hospital mediastinitis algorithm.
Poststernotomy mediastinitis, also commonly called deep sternal wound infection, is one of the most feared complications in patients undergoing cardiac surgery. The overall incidence ofExpand
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Effects of vacuum‐assisted closure therapy on inguinal wound edge microvascular blood flow
Vacuum‐assisted closure (VAC) therapy has been shown to facilitate wound healing. Data on the mechanisms are scarce, although beneficial effects on blood flow and granulation tissue formation haveExpand
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Clinical outcome after poststernotomy mediastinitis: vacuum-assisted closure versus conventional treatment.
BACKGROUND The conventional treatment for poststernotomy mediastinitis usually involves surgical revision, closed irrigation, or reconstruction with omentum or pectoral muscle flaps. Recently,Expand
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Evidence-based recommendations for the use of Negative Pressure Wound Therapy in traumatic wounds and reconstructive surgery: steps towards an international consensus.
Negative pressure wound therapy (NPWT) has become widely adopted over the last 15 years and over 1000 peer reviewed publications are available describing its use. Despite this, there remainsExpand
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Blood flow responses in the peristernal thoracic wall during vacuum-assisted closure therapy.
BACKGROUND Vacuum-assisted closure (VAC) therapy is a recently introduced method for the treatment of poststernotomy mediastinitis. The aim of this study was to examine the effects of negativeExpand
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Clinical transplantation of initially rejected donor lungs after reconditioning ex vivo.
BACKGROUND A major problem in clinical lung transplantation is the shortage of donor lungs. Only about 20% of donor lungs are accepted for transplantation. A method to evaluate and recondition lungsExpand
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First human transplantation of a nonacceptable donor lung after reconditioning ex vivo.
PURPOSE This article describes an ex vivo method to recondition and transplant rejected donor lungs. DESCRIPTION A 19-year-old man was brain dead after a traffic accident. A roentgenogram showedExpand
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Evidence-based recommendations for negative pressure wound therapy: treatment variables (pressure levels, wound filler and contact layer)--steps towards an international consensus.
Negative pressure wound therapy (NPWT) is becoming a commonplace treatment in many clinical settings. New devices and dressings are being introduced. Despite widespread adoption, there remainsExpand
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Wound Edge Microvascular Blood Flow during Negative-Pressure Wound Therapy: Examining the Effects of Pressures from –10 to –175 mmHg
Background: Negative-pressure wound therapy is believed to accelerate wound healing by altered wound edge microvascular blood flow. The current standard negative pressure is –125 mmHg. However, thisExpand
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Micro- and Macromechanical Effects on the Wound Bed of Negative Pressure Wound Therapy Using Gauze and Foam
Negative pressure wound therapy (NPWT) results in 2 types of tissue deformation, macrodeformation (ie, wound contraction) and microdeformation (ie, the interaction of tissue and dressing on aExpand
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