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Rhodium-Catalyzed Asymmetric Conjugate Additions of Boronic Acids Using Monodentate Phosphoramidite Ligands
Monodentate phosphoramidites have been used for the first time as chiral ligands in the Rh-catalyzed enantioselective conjugate addition of arylboronic acids to enones, unsaturated esters, lactones,Expand
Highly Enantioselective Catalytic Conjugate Addition and Tandem Conjugate Addition–Aldol Reactions of Organozinc Reagents
Although efficient catalysts for a number of asymmetric carbon carbon formations are known to date, a highly enantioselective catalytic version of the conjugate addition of organometallic reagents toExpand
Enantioselective Catalytic Conjugate Addition of Dialkylzinc Reagents using Copper-Phosphoramidite Complexes; Ligand Variation and Non-linear Effects
Abstract A variety of new chiral phosphoramidites was synthesised and tested in the copper-catalysed enantioselective conjugate addition of diethylzinc to cyclohexenone and chalcone in order toExpand
A highly enantioselective intramolecular Heck reaction with a monodentate ligand.
TLDR
Excellent enantioselectivities up to 96% ee are reached for the first time in a Heck reaction with monodentate ligands. Expand
Highly Enantioselective Catalytic Conjugate Additions to Cyclohexadienones
Enantioselective copper phosphoramidite-catalyzed conjugate addition of dialkylzinc reagents (R2Zn) to several 4,4-disubstituted cyclohexadienones was achieved with dr's up to 99/1 and ee's up to 99%.
Rhodium-catalyzed asymmetric conjugate additions of boronic acids using monodentate phosphoramidite ligands.
Monodentate phosphoramidites have been used for the first time as chiral ligands in the Rh-catalyzed enantioselective conjugate addition of arylboronic acids to enones, unsaturated esters, lactones,Expand
A catalytic enantioselective route to cis- and trans-3,4,4,5-tetrasubstituted cyclohexanones; remarkable chiral catalyst control in sequential catalytic 1,4-additions to cyclohexadienones
Asymmetric copper-phosphoramidite catalysed conjugate addition of Et2Zn to easily accessible, nearly enantiomerically pure cyclohexenones 2 and 4 was performed. Depending on the enantiomer of theExpand
Copper‐catalyzed Enantioselective Conjugate Addition Reactions of Organozinc Reagents
Conjugate addition (1,4-addition) of carbon nucleophiles to a; b-unsaturated compounds is one of the most important carbon–carbon bond-forming strategies in synthetic organic chemistry [1]. TheExpand
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