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Early Second-Trimester Serum MiRNA Profiling Predicts Gestational Diabetes Mellitus
Background Gestational diabetes mellitus (GDM) is one type of diabetes that presents during pregnancy and significantly increases the risk of a number of adverse consequences for the fetus and… Expand
A sperm GPI-anchored protein elicits sperm-cumulus cross-talk leading to the acrosome reaction
- L. Yin, C. M. Chung, +23 authors H. C. Chan
- Biology, Medicine
- Cellular and Molecular Life Sciences
- 21 January 2009
Abstract.The acrosome reaction has long been thought to be induced by the zona pellucida. Here we report the identification and function of a novel human sperm glycosylphosphatidylinositol… Expand
Identification of several proteins involved in regulation of sperm motility by proteomic analysis.
- Chun Zhao, R. Huo, F. Wang, Min Lin, Z. Zhou, J. Sha
- Biology, Medicine
- Fertility and sterility
- 1 February 2007
Proteomic technology was used to compare sperm protein expression profiles in asthenozoospermic patients with that of normozoospermic donors and 10 differentially expressed proteins were identified.… Expand
Proteomic-based identification of maternal proteins in mature mouse oocytes
BackgroundThe mature mouse oocyte contains the full complement of maternal proteins required for fertilization, reprogramming, zygotic gene activation (ZGA), and the early stages of embryogenesis.… Expand
Systematic identification of genes with a cancer-testis expression pattern in 19 cancer types
Cancer-testis (CT) genes represent the similarity between the processes of spermatogenesis and tumorigenesis. It is possible that their selective expression pattern can help identify driver genes in… Expand
A two-dimensional electrophoresis reference map of human ovary
The ovary plays a central role in oogenesis and gonadal hormone secretion. Proteomic analysis is a valuable approach for gaining an increased understanding of the molecular nature of the ovary. In… Expand
Proteomic analysis of effect of hyperthermia on spermatogenesis in adult male mice.
We characterized cellular and molecular mechanisms involved in spermatogenesis following short-term heat exposure of murine testis. For these studies, we utilized a proteomic approach with… Expand
Evaluation of Blastomere Biopsy Using a Mouse Model Indicates the Potential High Risk of Neurodegenerative Disorders in the Offspring*
Preimplantation genetic diagnosis (PGD), used in clinical practice, is offered to couples that may suffer from a monogenetic disorder, chromosome aneuploidy, or X-linked disease. However, blastomere… Expand
A cancer-testis non-coding RNA LIN28B-AS1 activates driver gene LIN28B by interacting with IGF2BP1 in lung adenocarcinoma
Our previous work found cancer-testis (CT) genes as a new source of epi-driver candidates of cancer. LIN28B was a CT gene, but the “driver” ability and the activation mechanism in lung adenocarcinoma… Expand
MicroRNA-383 is a tumor suppressor and potential prognostic biomarker in human non-small cell lung caner.
- Y. Shang, A. Zang, +10 authors J. Jiang
- Biomedicine & pharmacotherapy = Biomedecine…
- 1 October 2016
PURPOSE The purpose of this study is to examine the expression and clinical significance microRNA-383 (miR-383) in non-small cell lung cancer (NSCLC) both in vitro and in vivo. METHODS Tumorous… Expand