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International Consensus Recommendations on the Management of Patients With Nonvariceal Upper Gastrointestinal Bleeding
TLDR
Recommendations emphasize early risk stratification, by using validated prognostic scales, and early endoscopy, whereas data support attempts to dislodge clots with hemostatic, pharmacologic, or combination treatment of the underlying stigmata.
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Fecal Microbiota Transplantation for Clostridium difficile Infection: Systematic Review and Meta-Analysis
TLDR
FMT holds considerable promise as a therapy for recurrent CDI but well-designed, RCTs and long-term follow-up registries are still needed before this approach can be widely advocated.
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Speed of healing and symptom relief in grade II to IV gastroesophageal reflux disease: a meta-analysis.
TLDR
More complete esophagitis healing and heartburn relief is observed with PPIs vs. H2RAs and occurs nearly twice as fast.
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Appropriate acid suppression for the management of gastro-oesophageal reflux disease.
TLDR
Preliminary meta-analysis shows that the healing rate of erosive oesophagitis at 8 weeks by antisecretory agents is directly related to the duration of suppression of gastric acid secretion achieved over a 24-hour period.
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Meta-analysis of the relationship between Helicobacter pylori seropositivity and gastric cancer.
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Guidelines for the management of Helicobacter pylori infection
TLDR
These guidelines are developed under the auspices of the American College of Gastroenterology and its practice parameters committee and may be updated with pertinent scientific developments at a later time.
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Helicobacter pylori in developing countries. World Gastroenterology Organisation Global Guideline.
TLDR
Therapeutic vaccination is probably the only strategy that would make a decisive difference in the prevalence and incidence of Hp throughout the world, and would be a test-and-treat strategy for those who are at risk for peptic ulcer disease or gastric cancer, as well as for those with troublesome dyspepsia.
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Role of Helicobacter pylori infection and non-steroidal anti-inflammatory drugs in peptic-ulcer disease: a meta-analysis
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Second Asia–Pacific Consensus Guidelines for Helicobacter pylori infection
TLDR
It was recommended that H. pylori infection should be tested for and eradicated prior to long‐term aspirin or non‐steroidal anti‐inflammatory drug therapy in patients at high risk for ulcers and ulcer‐related complications and in communities with high incidence of gastric cancer prevention.
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Helicobacter pylori eradication therapy to prevent gastric cancer in healthy asymptomatic infected individuals: systematic review and meta-analysis of randomised controlled trials
TLDR
Limited, moderate quality evidence is provided that searching for and eradicating H pylori reduces the incidence of gastric cancer in healthy asymptomatic infected Asian individuals, but these data cannot necessarily be extrapolated to other populations.
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