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Estimation of levels of gene flow from DNA sequence data.

- R. Hudson, M. Slatkin, W. Maddison
- Biology, Medicine
- Genetics
- 1 October 1992

We compare the utility of two methods for estimating the average levels of gene flow from DNA sequence data. One method is based on estimating FST from frequencies at polymorphic sites, treating each… Expand

1,434 276- PDF

Generating samples under a Wright-Fisher neutral model of genetic variation

- R. Hudson
- Biology, Computer Science
- Bioinform.
- 1 February 2002

TLDR

2,346 183

A statistical test for detecting geographic subdivision.

A statistical test for detecting genetic differentiation of subpopulations is described that uses molecular variation in samples of DNA sequences from two or more localities. The statistical… Expand

898 183- PDF

A test of neutral molecular evolution based on nucleotide data.

- R. Hudson, M. Kreitman, M. Aguadé
- Biology, Medicine
- Genetics
- 1 May 1987

The neutral theory of molecular evolution predicts that regions of the genome that evolve at high rates, as revealed by interspecific DNA sequence comparisons, will also exhibit high levels of… Expand

1,680 177- PDF

Statistical properties of the number of recombination events in the history of a sample of DNA sequences.

Some statistical properties of samples of DNA sequences are studied under an infinite-site neutral model with recombination. The two quantities of interest are R, the number of recombination events… Expand

1,590 152

Pairwise comparisons of mitochondrial DNA sequences in stable and exponentially growing populations.

- M. Slatkin, R. Hudson
- Biology, Medicine
- Genetics
- 1 October 1991

We consider the distribution of pairwise sequence differences of mitochondrial DNA or of other nonrecombining portions of the genome in a population that has been of constant size and in a population… Expand

2,131 128- PDF

A new statistic for detecting genetic differentiation.

- R. Hudson
- Biology, Medicine
- Genetics
- 1 August 2000

A new statistic for detecting genetic differentiation of subpopulations is described. The statistic can be calculated when genetic data are collected on individuals sampled from two or more… Expand

556 126- PDF

LIAN 3.0: detecting linkage disequilibrium in multilocus data

- B. Haubold, R. Hudson
- Mathematics, Medicine
- Bioinform.
- 1 September 2000

TLDR

487 96

Two-locus sampling distributions and their application.

- R. Hudson
- Biology, Medicine
- Genetics
- 1 December 2001

Methods of estimating two-locus sample probabilities under a neutral model are extended in several ways. Estimation of sample probabilities is described when the ancestral or derived status of each… Expand

502 69- PDF

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