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Estimation of levels of gene flow from DNA sequence data.
We compare the utility of two methods for estimating the average levels of gene flow from DNA sequence data. One method is based on estimating FST from frequencies at polymorphic sites, treating eachExpand
  • 1,434
  • 276
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Generating samples under a Wright-Fisher neutral model of genetic variation
  • R. Hudson
  • Biology, Computer Science
  • Bioinform.
  • 1 February 2002
A Monte Carlo computer program is available to generate samples drawn from a population evolving according to a Wright-Fisher neutral model. Expand
  • 2,346
  • 183
A statistical test for detecting geographic subdivision.
A statistical test for detecting genetic differentiation of subpopulations is described that uses molecular variation in samples of DNA sequences from two or more localities. The statisticalExpand
  • 898
  • 183
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A test of neutral molecular evolution based on nucleotide data.
The neutral theory of molecular evolution predicts that regions of the genome that evolve at high rates, as revealed by interspecific DNA sequence comparisons, will also exhibit high levels ofExpand
  • 1,680
  • 177
  • PDF
Statistical properties of the number of recombination events in the history of a sample of DNA sequences.
Some statistical properties of samples of DNA sequences are studied under an infinite-site neutral model with recombination. The two quantities of interest are R, the number of recombination eventsExpand
  • 1,590
  • 152
Pairwise comparisons of mitochondrial DNA sequences in stable and exponentially growing populations.
We consider the distribution of pairwise sequence differences of mitochondrial DNA or of other nonrecombining portions of the genome in a population that has been of constant size and in a populationExpand
  • 2,131
  • 128
  • PDF
A new statistic for detecting genetic differentiation.
  • R. Hudson
  • Biology, Medicine
  • Genetics
  • 1 August 2000
A new statistic for detecting genetic differentiation of subpopulations is described. The statistic can be calculated when genetic data are collected on individuals sampled from two or moreExpand
  • 556
  • 126
  • PDF
Gene genealogies and the coalescent process.
  • 1,948
  • 111
LIAN 3.0: detecting linkage disequilibrium in multilocus data
LIAN is a program to test the null hypothesis of linkage equilibrium for multilocus data with Monte Carlo and algebraic methods. Expand
  • 487
  • 96
Two-locus sampling distributions and their application.
  • R. Hudson
  • Biology, Medicine
  • Genetics
  • 1 December 2001
Methods of estimating two-locus sample probabilities under a neutral model are extended in several ways. Estimation of sample probabilities is described when the ancestral or derived status of eachExpand
  • 502
  • 69
  • PDF