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A Human Protein Complex Homologous to the Drosophila MSL Complex Is Responsible for the Majority of Histone H4 Acetylation at Lysine 16
TLDR
It is found that reduction in the levels of hMSLs and acetylation of H4 at lysine 16 are correlated with reduced transcription of some genes and with a G2/M cell cycle arrest. Expand
Three-dimensional graphene foam as a biocompatible and conductive scaffold for neural stem cells
TLDR
Graphene foam, a 3D porous structure, is used as a novel scaffold for NSCs in vitro and phenotypic analysis indicated that 3D-GFs can enhance the NSC differentiation towards astrocytes and especially neurons. Expand
A Selective Phenelzine Analogue Inhibitor of Histone Demethylase LSD1
TLDR
Bizine was found to be effective at modulating bulk histone methylation in cancer cells, and ChIP-seq experiments revealed a statistically significant overlap in the H3K4 methylation pattern of genes affected by bizine and those altered in LSD1–/– cells, suggesting potential applications in neurodegenerative disease. Expand
The pathologic characteristics of breast cancer in China and its shift during 1999–2008: A national‐wide multicenter cross‐sectional image over 10 years
TLDR
Breast cancer in China showed more aggressive behavior than those in western countries, although tumor size and stage at diagnosis decreased by year during 1999–2008, and addressed the urgent needs for employ race‐specific breast cancer screen, diagnosis methods, and therapeutic models in China. Expand
Determination of vincristine in infant plasma by liquid chromatography-atmospheric pressure chemical ionization-mass spectroscopy.
TLDR
An LC-MS method using APCI has been developed and validated for the determination of the anticancer drug vincristine in human plasma, using vinblastine as internal standard, and has been used to measure plasma concentrations of vINCristine from 0.08 to 24 h post bolus in 29 infants. Expand
Nucleoside transporter expression and function in cultured mouse astrocytes
TLDR
Astrocytes are accordingly well suited for both intense nucleoside metabolism and metabolism‐independent uptake to terminate neuromodulator effects of adenosine and guanosine. Expand
Evaluation of the effect of the structure of bacterial cellulose on full thickness skin wound repair on a microfluidic chip.
TLDR
As an excellent biomaterial for wound healing, the BC film displays different properties on different sides, which provides a method to optimize the biocompatibility of wound dressings but also paves a new way to building heterogeneous BC-based biomaterials for complex tissue engineering. Expand
Recent progress of research on medicinal mushrooms, foods, and other herbal products used in traditional Chinese medicine
TLDR
This article will review selected herbal products used in traditional Chinese medicine, including medicinal mushrooms, with emphasis on the most recent progress in research for the period of 2003 to 2011. Expand
Nitrification activity and putative ammonia-oxidizing archaea in acidic red soils
TLDR
Nitrification activity change coupled well with abundance and composition changes of archaeal amoA genes, particularly for acidic BF and BFA soils, suggesting that AOA play important roles in ammonia oxidation in acidic red soils tested in this study. Expand
Evaluation of phytoremediation potential of five Cd (hyper)accumulators in two Cd contaminated soils.
TLDR
In summary, acidic soil was of higher potential to recover from Cd contamination by phytoextraction, while in the alkaline soil, S. plumbizincicola showed potential for Cd phy toextraction. Expand
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