R. Hofmann-Lehmann

Publications51
h-index21
Citations1,554
Highly Influential Citations42
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2008 American Association of Feline Practitioners' feline retrovirus management guidelines
Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) are among the most common infectious diseases of cats. Although vaccines are available for both viruses, identification and… Expand
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Serum protein concentrations from clinically healthy horses determined by agarose gel electrophoresis.
BACKGROUND Serum protein electrophoresis is a useful screening test in equine laboratory medicine. The method can provide valuable information about changes in the concentrations of albumin and… Expand
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Live attenuated, nef-deleted SIV is pathogenic in most adult macaques after prolonged observation
Objective: A live attenuated SIV vaccine strain, termed SIVmac239Δ3 and containing large deletions in nef, vpr and the negative regulatory element, was previously shown to cause AIDS mostly in… Expand
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Correction: A canine distemper virus epidemic in Serengeti lions (Panthera leo) (Nature (1996) 379 (441-445))
Nature 379, 441–445 (1996) In this Letter, the received and accepted dates for the manuscript were incorrectly listed as being in 1994, instead of 1995. The correct dates are: received 2 October;… Expand
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Surveillance using serological and molecular methods for the detection of infectious agents in captive Brazilian neotropic and exotic felids
The aim of the current study was to investigate the exposure of captive wild felids to various infectious pathogens using serological and molecular methods. One hundred and fifty-nine neotropic… Expand
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Sensitive and robust one-tube real-time reverse transcriptase-polymerase chain reaction to quantify SIV RNA load: comparison of one- versus two-enzyme systems.
Plasma viral RNA load is a key parameter in disease progression of lentiviral infections. To measure simian immunodeficiency virus (SIV) RNA loads, we have established a quantitative one-tube assay… Expand
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Post-exposure prophylaxis with human monoclonal antibodies prevented SHIV89.6P infection or disease in neonatal macaques
Background: The majority of infants infected through maternal transmission acquire the virus during birth or postpartum through breastfeeding: mucosal exposure is considered to be a major route of… Expand
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Fat intake modifies vascular responsiveness and receptor expression of vasoconstrictors: implications for diet-induced obesity.
OBJECTIVE Angiotensin II (Ang II), endothelin-1 (ET-1) and reactive oxygen species (ROS) have been implicated in the development of pathologic changes associated with obesity including hypertension… Expand
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Quantitation of simian cytokine and beta-chemokine mRNAs, using real-time reverse transcriptase-polymerase chain reaction: variations in expression during chronic primate lentivirus infection.
Cytokines and beta-chemokines are important mediators of the immune system and are expressed in many infectious diseases. To study cytokine and beta-chemokine profiles during pathogenesis of… Expand
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Passive immunization against oral AIDS virus transmission: An approach to prevent mother‐to‐infant HIV‐1 transmission?
To develop immunoprophylaxis regimens against mother‐to‐child human immunodeficiency virus type 1 (HIV‐1) transmission, we established a simian–human immunodeficiency virus (SHIV) model in neonatal… Expand
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