R. Higgs

Publications19
h-index10
Citations628
Highly Influential Citations3
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Lower esophageal sphincter and gastric acid response to intravenous infusions of synthetic human gastrin I heptadecapeptide.
Human gastrin I heptadecapeptide was administered by constant intravenous infusion to 7 adult male volunteers without gastrointestinal disease, and serum gastrin concentrations and responses of the… Expand
  • 31
  • 1
Hypotheses on the origin of the Mediterranean Basin: Magnetic data
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  • 1
Magnetic anomaly map of North America
Data presented on the magnetic anomaly map in the continental areas have largely been derived from published map sources. However, these maps for the most part have been digitized and subjected to… Expand
  • 60
  • 1
Experimental esophagitis in cats impairs lower esophageal sphincter pressure.
We studied the effect of esophageal inflammation on lower esophageal sphincter (LES) pressure in cats by measuring LES pressure and taking mucosal biopsies before and after the development of… Expand
  • 162
Studies on the mechanism of esophagitis-induced lower esophageal sphincter hypotension in cats.
Perfusion of 0.1 n HC1 5 cm above the lower esophageal sphincter (LES) in cats for 30 min on 4 consecutive days produced biopsy-documented esophagitis and marked decreases in LES pressure. Using this… Expand
  • 63
Gastric alkalinization. Effect on lower-esophageal-sphincter pressure and serum gastrin.
  • 94
Colonoscopy associated bacteremia.
Fifty-two patients undergoing uneventful diagnostic colonoscopy with or without polypectomy and biopsy were evaluated for evidence of bacteremia during and after the procedure. In only two instances… Expand
  • 34
Evaluation of the effect of fundoplication on the incompetent lower esophageal sphincter.
The increase in tension of the gastroesophageal high pressure zone after fundoplication and hiatal hernia repair could represent either a mechanical effect or enhanced smooth muscle tone of the lower… Expand
  • 12
Lower esophageal sphincter response to oral administration of cimetidine in normal subjects.
Anithistamines that specifically block the gastric and secretory action of histamine have recently been developed. One of these H2-receptor blockers, metiamide, has been found to increase lower… Expand
  • 25
Assessment of simple methods of measuring intestinal transit times in children with gastroenteritis.
Intestinal transit times in children less than 3 years old with gastroenteritis were measured using carmine suspension and radioopaque pellets. Carmine transit times were short as expected in the… Expand
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