• Publications
  • Influence
Subcortical and cortical brain activity during the feeling of self-generated emotions
In a series of [15O]PET experiments aimed at investigating the neural basis of emotion and feeling, 41 normal subjects recalled and re-experienced personal life episodes marked by sadness, happiness,Expand
  • 1,843
  • 115
  • PDF
A neural basis for lexical retrieval
Two parallel studies using positron emission tomography, one conducted in neurological patients with brain lesions, the other in normal individuals, indicate that the normal process of retrieving words that denote concrete entities depends in part on multiple regions of the left cerebral hemisphere, located outside the classic language areas. Expand
  • 1,018
  • 58
  • PDF
A neural basis for lexical retrieval
Nature 380, 499-505 (1996) AN ambiguity was introduced during editing into the opening sentence of the heading of this Article. This should read "Two parallel studies, one conducted in neurologicalExpand
  • 422
  • 32
  • PDF
Remembering the past: two facets of episodic memory explored with positron emission tomography.
OBJECTIVE This study used positron emission tomography to examine two kinds of personal memory that are used in psychiatric evaluation: focused episodic memory (recall of past experience, employed inExpand
  • 533
  • 25
A role for left temporal pole in the retrieval of words for unique entities
Both lesion and functional imaging studies have implicated sectors of high‐order association cortices of the left temporal lobe in the retrieval of words for objects belonging to varied conceptualExpand
  • 276
  • 21
  • PDF
Schizophrenia and cognitive dysmetria: a positron-emission tomography study of dysfunctional prefrontal-thalamic-cerebellar circuitry.
Patients suffering from schizophrenia display subtle cognitive abnormalities that may reflect a difficulty in rapidly coordinating the steps that occur in a variety of mental activities. WorkingExpand
  • 553
  • 19
  • PDF
Cerebral blood flow changes associated with attribution of emotional valence to pleasant, unpleasant, and neutral visual stimuli in a PET study of normal subjects.
OBJECTIVE To assist in the development of a model for the psychopathology of emotions, the present study sought to identify the neural circuits associated with the evaluation of visual stimuli forExpand
  • 311
  • 19
Cerebral blood flow and personality: a positron emission tomography study.
OBJECTIVE This study sought to describe brain regions associated with the personality dimension of introversion/extraversion. METHOD Measures of cerebral blood flow (CBF) were obtained from 18Expand
  • 188
  • 18
Neural mechanisms of anhedonia in schizophrenia: a PET study of response to unpleasant and pleasant odors.
CONTEXT Loss of the capacity to experience pleasure (anhedonia) is a core clinical feature of schizophrenia. Although functional imaging techniques have been successful in identifying the neuralExpand
  • 231
  • 14
  • PDF
Hypofrontality in schizophrenia: distributed dysfunctional circuits in neuroleptic-naïve patients
BACKGROUND There have been reports that patients with schizophrenia have decreased metabolic activity in prefrontal cortex. However, findings have been confounded by medication effects, chronicExpand
  • 563
  • 13