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Chondrocyte Viability in Refrigerated Osteochondral Allografts Used for Transplantation within the Knee
TLDR
Data indicate that refrigerated osteochondral allografts can be maintained for up to 44 days with average chondrocyte viability of 67%, indicating less matrix staining in grafts refrigerated longer after harvest.
Free radical production in hypoxic pulmonary artery smooth muscle cells.
TLDR
Findings show that PASMCs acutely exposed to hypoxia exhibit a marked increase in intracellular DCF fluorescence, suggestive of reactive oxygen or nitrogen species production.
Toxocara canis: failure to find IgE receptors (Fc epsilon R) on eosinophils from infected mice suggests that murine eosinophils do not kill helminth larvae by an IgE-dependent mechanism.
TLDR
Eosinophils obtained by bronchoalveolar lavage from the lungs of mice infected with Toxocara canis were characterized by flow cytometry with respect to cytophilic antibodies and surface Fc receptors and may indicate different functional activities for mouse BAL eosInophils in helminth infections.
Activated neutrophil-mediated sickle red blood cell adhesion to lung vascular endothelium: role of phosphatidylserine-exposed sickle red blood cells.
TLDR
It is concluded that ANs enhance the adhesion of SRBCs to vascular endothelium by increasing red blood cell membrane externalization of PS.
Intracellular calcium puffs in osteoclasts.
TLDR
It is concluded that [Ca(2+)](i) transients in osteoclast are increased in acid-secreting osteoclasts, and that the puffs occur mainly near the acid-transporting membrane.
Increased oxygen tensions influence subset composition of the cellular immune system in aged mice.
TLDR
The suggestion is made that the immune system has a reserve capacity that can be influenced by oxygen and is theoretically capable of being pharmacologically manipulated to assist patients with altered immune systems to promote defense mechanisms or, under certain circumstances, reduce autoimmunity.
THE STRUCTURAL BASIS FOR BINDING OF COMPLEMENT BY IMMUNOGLOBULIN M
TLDR
Structural considerations and sequence overlaps suggest that the amino-terminal side of the CH4 domain (24 amino acid residues) might be responsible for fixing C1.
Modulation of human T cell production of migration inhibitory lymphokines by cytokines derived from human leukocyte dialysates.
TLDR
The amplifiers were found to increase LIF and MIF production by antigen- or alloantigen-stimulated human peripheral blood lymphocytes in a dose-dependent fashion and demonstrated that although antigen- Stimulated T4 and T8 cell subpopulations could produce LIF activity under the assay conditions employed, amplification of lymphokine production by modulator was only observed with the T4 subset.
The Functional Heterogeneity of Macrophages
TLDR
Macrophages are morphologically and functionally diverse cells that play vital roles in homeostasis and in host defense reactions against foreign materials, microbial agents, and, possibly, neoplasms.
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