• Publications
  • Influence
Effect of Endoplasmic Reticulum Stress on Porcine Oocyte Maturation and Parthenogenetic Embryonic Development In Vitro1
TLDR
Results indicated that inhibition of ER stress enhanced porcine oocyte maturation and embryonic development by preventing ER stress-mediated apoptosis in vitro. Expand
Treatment of fetal fibroblasts with DNA methylation inhibitors and/or histone deacetylase inhibitors improves the development of porcine nuclear transfer-derived embryos.
TLDR
Results indicate that treatment of donor cells with 5-aza-dC, TSA, or TSA plus a low dose of 5-aze-dD could improve the blastocyst development of porcine cloned embryos. Expand
Detection of early pregnancy-specific proteins in Holstein milk.
TLDR
Western blot analysis showed that the levels of expression of lactoferrin and alpha1G T-type calcium channel subunit (alpha-1G) were higher in samples from pregnant than non-pregnant cattle, suggesting that assays for pregnancy-specific milk proteins may be used to diagnose pregnancy in cattle. Expand
Cardiovascular risk assessment of atypical antipsychotic drugs in a zebrafish model
TLDR
The zebrafish model facilitates determination of the heart beat rate, and may be an attractive screening tool for cardiovascular risk assessment of atypical antipsychotic drugs to understand the variations in response to QT‐prolonging drugs. Expand
A two‐dimensional electrophoresis reference map for the bovine placenta during late pregnancy
TLDR
The results revealed the composite profiles of key proteins in the bovine placenta during late pregnancy, which will shed light on placental function during pregnancy and assist with functional analysis of the proteins. Expand
Halogenated nucleotide labeling of nascent RNAs reveals dynamic transcription in growing pig oocytes
TLDR
It is shown that fluorouridine (FU), a halogenated nucleotide, can be successfully incorporated into synthesizing RNAs and detected using a specific monoclonal antibody and support the suitability of FU for studies on transcription‐related events in mammalian oocytes. Expand
Epigenetic characterization of the PBEF and TIMP-2 genes in the developing placentae of normal mice.
TLDR
It is suggested that epigenetic changes may regulate gene expression level in the developing placentae of normal mice and that inappropriate epigenetic reprogramming might be one cause of the abnormal placenta seen in cloned animals. Expand
Aberrant protein expression in the placenta of cloned mouse derived from embryonic stem cell.
Placentomegaly is a common phenotype in cloned mice. To assess differences in protein expression between placentae of cloned and uncloned mice, we used a proteomic approach involving 2-dimensionalExpand
Abnormal expression of TIMP-2, SOD, vimentin and PAI proteins in cloned bovine placentae.
TLDR
Western blot analysis suggests that key proteins of placental development are abnormally expressed in SCNT cloned bovine placentae, probably resulting in abnormal placental function and clonal mortality. Expand
...
1
2
3
...