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An antiinflammatory cum immunomodulatory piperidinylbenzopyranone from dysoxylum binectariferum : isolation, structure and total synthesis
Abstract (+)-cis -5,7-Dihydroxy-2-methyl-8-[4-(3-hydroxy-1-methyl) piperidinyl]-4 H -1-benzopyran-4-one was identified as the antiinflammatory cum immunomodulatory principle of the stem bark ofExpand
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Isolation, structure elucidation and synthesis of 1-deoxyforskolin
Abstract Isolation and structure elucidation of 1-deoxyforskolin ( 2 ), a minor forskolin related constituent, of the Indian herb Coleus forskohlii are described. The structure of 2 is confirmed byExpand
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NEW PROSTACYCLIN ANALOGS
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Aluminum Chloride as a Powerful Catalyst for the Preparation of O-Isopropylidene and O-Benzylidene Derivatives of Labdanes
Preparation de composes diversement proteges a partir de l'epoxy-8,13 pentahydroxy-1α,3β,6β,7β,9α labdene-14 one-11
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Microbial transformation of 1,9-dideoxyforskolin to forskolin
Abstract Screening of hydroxylating fungi provided a Scopuloriopsis species which transformed 7-deacetyl-1,9-dideoxyforskolin to 7-deacetyl-forskolin.
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Novel 1,9-dideoxyforskolin analogues through microbial transformations
Abstract Microbial transformations of 1,9-dideoxyforskolin ( 1 ) and 7-deacetyl-1,9-dideoxyforskolin ( 2 ) were carried out. Various mono- and di-hydroxylated derivatives were isolated and identified.
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Synthesis of metabolites of forskolin
Abstract Microbial and chemical transformations of 7-deacetylforskolin ( 5 ) are described, leading to 3β-hydroxyforskolin ( 2 ) and its derivatives, which have been found to be metabolites ofExpand
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Maclafungin, a new antifungal macrocyclic lactone from Actinomycete sp. Y-8521050
Abstract A new antifungal macrocyclic lactone maclafungin, belonging to the oligomycin class has been isolated from an actinomycete sp. Y-8521050. The antibiotic, having a molecular formula ofExpand
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