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Pacidamycins, a novel series of antibiotics with anti-Pseudomonas aeruginosa activity. II. Isolation and structural elucidation.
A novel class of antibiotics was isolated from cultures of Streptomyces coeruleorubidus strain AB 1183F-64. The antimicrobial activity of the pacidamycins is selective against Pseudomonas aeruginosa.Expand
Calbistrins, novel antifungal agents produced by Penicillium restrictum. II. Isolation and elucidation of structure.
TLDR
NMR studies revealed that the calbistrins each contain a carboxylic acid conjugated tetraene attached through an aliphatic ester linkage to a hexahydronaphthalene system. Expand
Phenelfamycins, a novel complex of elfamycin-type antibiotics. II. Isolation and structure determination.
TLDR
A novel complex of elfamycin-type antibiotics has been isolated from submerged fermentation of either Streptomyces violaceoniger AB 999F-80 or Streptococcal AB 1047T-33 using a variety of spectroscopic techniques, including extensive use of 1D and 2D NMR spectroscopy. Expand
Pacidamycins, a novel series of antibiotics with anti-Pseudomonas aeruginosa activity. I. Taxonomy of the producing organism and fermentation.
The pacidamycins are a new complex of nucleosidyl-peptide antibiotics with highly specific activity against Pseudomonas aeruginosa. They are produced by Streptomyces coeruleorubidus AB 1183F-64 whichExpand
Pacidamycins, a novel series of antibiotics with anti-Pseudomonas aeruginosa activity. III. Microbiologic profile.
TLDR
The pacidamycins were inactive against P. aeruginosa in mouse protection test and the frequency of resistance to these compounds was less than 3.5 x 10(-6). Expand
Corynecandin: a novel antifungal glycolipid from Coryneum modonium.
Novel triterpene sulfates from Fusarium compactum using a rhinovirus 3C protease inhibitor screen.
Two novel triterpene sulfates have been isolated from Fusarium compactum by bioactivity-directed fractionation using an assay which measures the inhibition of proteolytic activity of rhinovirus 3CExpand
Discovery of saricandin, a novel papulacandin, from a Fusarium species.
Dibefurin, a novel fungal metabolite inhibiting calcineurin phosphatase activity.
The novel calcineurin inhibitor, dibefurin, has been isolated from the fungal culture AB 1650I-759. The isolation was bioactivity-directed fractionation using an assay which measures the phosphataseExpand
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