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Shear stress and pressure modulate saphenous vein remodeling ex vivo.
Vein graft failure remains an important clinical challenge, but factors contributing to vein graft failure have not clearly been defined. We investigated the role of the mechanical environment inExpand
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Mechanical Environment, Donor Age, and Presence of Endothelium Interact to Modulate Porcine Artery Viability Ex Vivo
AbstractThough ex vivo culture of arteries is a widely used model of native arteries and is closely aligned with efforts to generate tissue-engineered arteries, the effects of culture conditions onExpand
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Mechanical properties of native and ex vivo remodeled porcine saphenous veins.
When grafted into an arterial environment in vivo, veins remodel in response to the new mechanical environment, thereby changing their mechanical properties and potentially impacting their patency asExpand
  • 48
Kinetics of protein depletion in rat bronchoalveolar lavage fluid following in vitro exposure to nitrogen dioxide.
Upon inhalation, nitrogen dioxide (NO(2)), a strong oxidizing agent, first comes into contact and reacts with the fluids lining the airways of the respiratory tract. These respiratory tract liningExpand
  • 4
Noninvasive determination of perfused artery dimensions ex vivo using a pressure-diameter relationship.
Based on the decisive effects of the hemodynamic and mechanical environments on the development and remodeling of arteries in vivo, several groups have cultured tissue-engineered vessels and excisedExpand
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FLEXIBLE OR CEMENT CONCRETE PAVEMENT ON THE ADRIATIC MOTORWAY. IN: PROCEEDINGS - 1ST SYMPOSIUM ON TRAFFIC AND ENGINEERING ASPECTS OF ADRIATIC MOTORWAY, DUBROVNIK, 13-15 NOVEMBER 1989
The paper presents a method of parallel analysis of global construction and maintenance costs of flexible and cement concrete pavements. The results of an analysis concerning cost differences,Expand
Noninvasive determination of perfused blood vessel dimensions using a pressure-diameter relationship
Based on the decisive effects of the hemodynamic/mechanical environments on the development and remodeling of arteries in vivo, several groups have cultured tissue-engineered vessels in variousExpand
A simple, non-invasive technique to monitor the biomechanical properties of ex vivo cultured blood vessels
  • R. Gusic, K. Gooch
  • Computer Science
  • Proceedings of the Second Joint 24th Annual…
  • 23 October 2002
In an effort to elucidate the mechanical and biochemical factors that play a role in the remodeling of blood vessels, researchers have developed ex vivo perfusion systems to study the response ofExpand
Directional secretion of human growth hormone by genetically-modified endothelial cells
Endothelial cells, which line the lumen of blood vessels, are in a useful location to deliver proteins to the blood. The authors have studied the directional secretion of human growth hormone (hGH)Expand