Characterization of nasal spray pumps and deposition pattern in a replica of the human nasal airway.
Detailed deposition information from the turbinate region indicated that deposition was high toward the anterior portion where most deposition was concentrated on the inferior meatus, and the spray angle and droplet size of the nasal spray were found to be important in influencing the deposition pattern in the nasal airway.
In vivo measurements of nasal airway dimensions and ultrafine aerosol deposition in the human nasal and oral airways
Toxicity of inhaled plutonium dioxide in beagle dogs.
The biological effects of inhaled 238PuO2 over the life spans of 144 beagle dogs suggest that similar dose-related biological effects could be expected in humans accidentally exposed to 238PUO2.
COMPUTATIONAL FLUID DYNAMICS SIMULATIONS OF INSPIRATORY AIRFLOW IN THE HUMAN NOSE AND NASOPHARYNX
A three-dimensional, anatomically accurate representation of an adult human nasal cavity and nasopharynx was constructed and airflow was streamlined in the main nasal passages and complex in the vestibul...
Nasal Deposition of Ultrafine Particles in Human Volunteers and Its Relationship to Airway Geometry
- Yung-sung Cheng, H. Yeh, R. Guilmette, S. Simpson, K. Cheng, D. Swift
- Environmental Science
- 1 October 1996
ABSTRACT Very large and very small particles most often deposit in the nasal airways. Human volunteers have often been used in deposition studies using particles > 0.5 μm, whereas physical airway…
Characterization of phagolysosomal simulant fluid for study of beryllium aerosol particle dissolution.
Implanted depleted uranium fragments cause soft tissue sarcomas in the muscles of rats.
- F. Hahn, R. Guilmette, Mark D. Hoover
- Medicine, BiologyEnvironmental Health Perspectives
- 15 December 2001
The results indicate that DU fragments of sufficient size cause localized proliferative reactions and soft tissue sarcomas that can be detected with radiography in the muscles of rats.
Efficacy of 3,4,3-LI(1,2-HOPO) for decorporation of Pu, Am and U from rats injected intramuscularly with high-fired particles of MOX.
- F. Paquet, V. Chazel, P. Houpert, R. Guilmette, B. Muggenburg
- BiologyRadiation Protection Dosimetry
- 1 July 2003
Results confirm that LIHOPO is a good candidate for use after contamination with MOX, in combination with localised wound lavage or surgical treatment aimed at removing most of the contaminant at the wound site.
Distribution and retention of 241Am in the baboon.
The distribution, retention, and excretion of intravenously injected /sup 241/Am citrate have been investigated in a nonhuman primate and microlocalization of Am in various soft tissues indicates general agreement with results previously reported for other species.
Updating the ICRP human respiratory tract model.
- M. Bailey, E. Ansoborlo, R. Guilmette, F. Paquet
- Environmental ScienceRadiation Protection Dosimetry
- 1 November 2007
The review of absorption rates provides a database of parameter values from which consideration can be given to deriving typical values for default Types F, M and S materials, and element-specific rapid dissolution rates.