Cytotoxic activity of Brazilian Cerrado plants used in traditional medicine against cancer cell lines.
- M. D. de Mesquita, J. E. de Paula, L. Espindola
- BiologyJournal of Ethnopharmacology
- 25 June 2009
Two new peltogynoids from Acacia nilotica Delile with kinase inhibitory activity.
- A. Ahmadu, Agunu Abdulkarim, A. Skaltsounis
- ChemistryPlanta Medica
- 1 March 2010
Two new peltogynoids were isolated from the stem bark of Acacia nilotica (L.) Delile, together with the known triterpene lupenone, and the structures of the new compounds were established on the basis of their spectral data, mainly UV, NMR, and mass spectrometry.
Sesamolinol glucoside, disaminyl ether, and other lignans from sesame seeds.
- R. Grougnet, P. Magiatis, H. Laborie, D. Lazarou, A. Papadopoulos, A. Skaltsounis
- ChemistryJournal of Agricultural and Food Chemistry
- 11 January 2012
The application of a procedure based on XAD-4 adsorption resin permitted the obtainment of an enriched polyphenolic extract from Sesamum indicum seeds, which led to the identification of 12 lignans, 2 of them, (+)-sesamolinol-4'-O-β-D-glucoside and disaminyl ether, reported for the first time as natural compounds.
Chemical and Biological Investigation of Olive Mill Waste Water – OMWW Secoiridoid Lactones
- K. Vougogiannopoulou, M. Angelopoulou, L. Skaltsounis
- BiologyPlanta Medica
- 28 July 2015
An attempt to investigate the secoiridoid content of olive mill waste water is described with the aid of ultrahigh-performance liquid chromatography-electrospray ionization (±)-high-resolution mass spectrometry and centrifugal partition chromatography methods.
Collected mass spectrometry data on monoterpene indole alkaloids from natural product chemistry research
- Alexander E. Fox Ramos, P. Le Pogam, M. Beniddir
- ChemistryScientific Data
- 3 April 2019
A cumulative collection of 172 tandem mass spectrometry (MS/MS) spectra from multiple research projects conducted in eight natural product chemistry laboratories since the 1960s, these data can be used to guide the dereplication and targeting of new related monoterpene indole alkaloids within complex mixtures when applying computer-based approaches, such as molecular networking.
Bixin, an apocarotenoid isolated from Bixa orellana L., sensitizes human melanoma cells to dacarbazine-induced apoptosis through ROS-mediated cytotoxicity.
- Raimundo Gonçalves de Oliveira Júnior, A. Bonnet, Laurent Picot
- BiologyFood and Chemical Toxicology
- 7 February 2019
New lignans from the perisperm of Sesamum indicum.
- R. Grougnet, P. Magiatis, S. Mitaku, A. Terzis, F. Tillequin, A. Skaltsounis
- ChemistryJournal of Agricultural and Food Chemistry
- 4 October 2006
A procedure, based on XAD-4 adsorption resin, which permits the obtainment of enriched polyphenolic extracts from Sesamum indicum perisperm (coat) has been developed and the identification of 16 lignans, two of them, (+)-saminol and (+)-episesaminone-9-O-beta-D-sophoroside, have been isolated.
Sensitization of tumor cells to chemotherapy by natural products: A systematic review of preclinical data and molecular mechanisms.
- Raimundo Gonçalves de Oliveira Júnior, Alves Ferraz Christiane Adrielly, J. D. S. da Silva Almeida, R. Grougnet, V. Thiéry, Laurent Picot
- Biology, ChemistryFitoterapia
- 1 September 2018
Chemical Composition and Antimicrobial Activity of the Essential Oils of Anthospermum emirnense and Anthospermum perrieri (Rubiaceae)
- Sylvia Tiana Ralambonirina Rasoarivelo, R. Grougnet, B. Deguin
- Chemistry, MedicineChemistry and Biodiversity
- 1 January 2011
When tested for antimicrobial activity, both essential oils showed similar profiles and exhibited interesting minimal‐inhibitory‐concentration (MIC) values towards Bacillus subtilis, Chryseobacterium indologenes, Flavimonas oryzihabitans, and Yersinia enterocolitica.
Pyrrolizidine alkaloids in medicinal tea of Ageratum conyzoides
- Cristiane F. Bosi, D. Rosa, M. Biavatti
- Chemistry
- 1 May 2013
To date, there are no established safety guidelines on pyrrolizidine alkaloids-containing plants, and their use in Brazil, and thirteen phenolic compounds were identified, notably, methoxylated flavonoids and chromenes.
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