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The effects of ethanol administration on brush border membrane glycolipids in rat intestine.
Ethanol ingestion is well known to induce morphological and biochemical changes in intestine and is responsible for intestinal dysfunctions. Luminal surface of enterocytes is rich in glycolipids, butExpand
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Kinetics studies with fruit bromelain (Ananas comosus) in the presence of cysteine and divalent ions
The kinetics of cysteine and divalent ion modulation viz. Ca2+, Cu2+, Hg2+ of fruit bromelain (EC 3.4.22.33) have been investigated in the present study. Kinetic studies revealed that at pH 4.5,Expand
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Competing in a supply chain via full-refund and no-refund customer returns policies
In this paper, we address the problem in which a manufacturer in a supply chain supplies a product to two competing retailers. Both retailers, facing customer returns, must decide on prices for theExpand
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Coordinated secretion of alkaline phosphatase into serum and intestine in fat-fed rats.
BACKGROUND Fat feeding increases the activity of intestinal alkaline phosphatase in the serum. The mechanism underlying this increase is unknown. Surfactant-like particles (SLP) secreted byExpand
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Ethanol induced changes in glycosylation of mucins in rat intestine
The epithelial surface of intestinal tract is covered by a mucosal layer, which constitutes the first line of defense against exposure of a variety of exogenous or endogenous agents. This epithelialExpand
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Truce-Smiles rearrangement of substituted phenyl ethers.
The requirement of aryl ring activation by strong-electron withdrawing substituents in substrates for the intramolecular nucleophilic aromatic substitution reaction known as the Truce-SmilesExpand
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HUMAN SIALYLTRANSFERASES AND ITS INTERACTION WITH ANTICANCER PHYTOCHEMICALS
Altered expression of sialyltransferases is well documented in cancer. Traditional anticancer drugs, mostly focus on inhibiting tumor cell growth or killing tumor cells directly or indirectly;Expand
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Interaction of mouse intestinal P-glycoprotein with oral antidiabetic drugs and its inhibitors.
Type 2 diabetes (T2DM) is a progressive insulin secretory defect accompanied by resistance to insulin, and thereby making glycemic control a major concern in the treatment of these patients. OralExpand
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Glycosyltransferase inhibitors: A promising strategy to pave a path from laboratory to therapy
Abnormal glycosylation is a common feature in disease that typically results from misregulation in expression and/or activity of glycosyltransferases (GTs) and glycosidases. Interfering with theseExpand
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Comparative expression of potato proteinase inhibitor type II in an oxidative versus reductive cytosolic environment of Escherichia coli
Potato proteinase inhibitor type II (PI2) is an enzyme primarily expressed in potato tubers that suppresses the activity of serine proteases such as trypsin and chymotrypsin. PI2 is a disulfide-richExpand
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