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A Draft Sequence of the Neandertal Genome
Kissing Cousins Neandertals, our closest relatives, ranged across Europe and Southwest Asia before their extinction approximately 30,000 years ago. Green et al. (p. 710) report a draft sequence of… Expand
The complete genome sequence of a Neanderthal from the Altai Mountains
- Kay Prüfer, Fernando Racimo, +42 authors S. Pääbo
- 2013
Kay Prüfer, Fernando Racimo, Nick Patterson, Flora Jay, Sriram Sankararaman, Susanna Sawyer, Anja Heinze, Gabriel Renaud, Peter H. Sudmant, Cesare de Filippo, Heng Li, Swapan Mallick, Michael… Expand
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- 104
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Genetic history of an archaic hominin group from Denisova Cave in Siberia
Using DNA extracted from a finger bone found in Denisova Cave in southern Siberia, we have sequenced the genome of an archaic hominin to about 1.9-fold coverage. This individual is from a group that… Expand
A High-Coverage Genome Sequence from an Archaic Denisovan Individual
- M. Meyer, Martin Kircher, +31 authors S. Pääbo
- Biology, Medicine
- Science
- 12 October 2012
Ancient Genomics The Denisovans were archaic humans closely related to Neandertals, whose populations overlapped with the ancestors of modern-day humans. Using a single-stranded library preparation… Expand
The Transcriptional Landscape of the Mammalian Genome
- Piero Carninci, T. Kasukawa, +191 authors Y. Hayashizaki
- Biology, Medicine
- Science
- 2 September 2005
This study describes comprehensive polling of transcription start and termination sites and analysis of previously unidentified full-length complementary DNAs derived from the mouse genome. We… Expand
Whole-genome analyses resolve early branches in the tree of life of modern birds
- E. Jarvis, S. Mirarab, +102 authors Guo-Jie Zhang
- Medicine, Biology
- Science
- 12 December 2014
To better determine the history of modern birds, we performed a genome-scale phylogenetic analysis of 48 species representing all orders of Neoaves using phylogenomic methods created to handle… Expand
Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans
- B. P. Lewis, R. Green, S. Brenner
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 26 December 2002
To better understand the role of alternative splicing, we conducted a large-scale analysis of reliable alternative isoforms of known human genes. Each isoform was classified according to its splice… Expand
The Developmental Transcriptome of Drosophila melanogaster
- B. Graveley, Angela N. Brooks, +44 authors S. Celniker
- Biology, Medicine
- Nature
- 11 December 2010
Drosophila melanogaster is one of the most well studied genetic model organisms, nonetheless its genome still contains unannotated coding and non-coding genes, transcripts, exons, and RNA editing… Expand
Patterns of damage in genomic DNA sequences from a Neandertal
- Adrian W. Briggs, U. Stenzel, +8 authors S. Pääbo
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 11 September 2007
High-throughput direct sequencing techniques have recently opened the possibility to sequence genomes from Pleistocene organisms. Here we analyze DNA sequences determined from a Neandertal, a… Expand
Comparative genomics reveals insights into avian genome evolution and adaptation
- Guo-Jie Zhang, C. Li, +103 authors J. Wang
- Biology, Medicine
- Science
- 12 December 2014
Birds are the most species-rich class of tetrapod vertebrates and have wide relevance across many research fields. We explored bird macroevolution using full genomes from 48 avian species… Expand
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