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Systematic implementation of an advance directive program in nursing homes: a randomized controlled trial.
CONTEXT Although advance directives are commonly used in the community, little is known about the effects of their systematic implementation. OBJECTIVES To examine the effect of systematicallyExpand
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Probabilistic Analysis of Cost-Effectiveness Models: Choosing between Treatment Strategies for Gastroesophageal Reflux Disease
When choosing between mutually exclusive treatment options, it is common to construct a cost-effectiveness frontier on the cost-effectiveness plane that represents efficient points from among theExpand
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Effect of PCI on quality of life in patients with stable coronary disease.
BACKGROUND It has not been clearly established whether percutaneous coronary intervention (PCI) can provide an incremental benefit in quality of life over that provided by optimal medical therapyExpand
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A review of the cost of cardiovascular disease.
In Canada, 74,255 deaths (33% of all deaths) in 2003 were due to cardio-vascular disease (CVD). As one of the most costly diseases, CVD represents a major economic burden on health care systems. TheExpand
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Relation between severity of Alzheimer's disease and costs of caring.
BACKGROUND Data from the Canadian Study of Health and Aging (CSHA) were used to examine the relation between severity of Alzheimer's disease, as measured by the Mini-Mental State Examination (MMSE),Expand
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Effectiveness and safety of drug-eluting stents in Ontario.
BACKGROUND The placement of drug-eluting stents decreases the frequency of repeat revascularization procedures in patients undergoing percutaneous coronary intervention (PCI) in randomized clinicalExpand
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Cost-effectiveness of the Edwards SAPIEN transcatheter heart valve compared with standard management and surgical aortic valve replacement in patients with severe symptomatic aortic stenosis: a
OBJECTIVES The primary analysis estimated the cost-effectiveness of transfemoral transcatheter aortic valve implantation (Edwards SAPIEN heart valve; Edwards Lifesciences LLC, Irvine, Calif) comparedExpand
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A nurse-coordinated model of care versus usual care for stage 3/4 chronic kidney disease in the community: a randomized controlled trial.
BACKGROUND AND OBJECTIVES It is unclear how to optimally care for chronic kidney disease (CKD). This study compares a new coordinated model to usual care for CKD. DESIGN, SETTING, PARTICIPANTS, &Expand
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A randomized controlled trial of a pharmacist consultation program for family physicians and their elderly patients.
BACKGROUND Pharmacists can improve patient outcomes in institutional and pharmacy settings, but little is known about their effectiveness as consultants to primary care physicians. We examinedExpand
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Cost-Effectiveness of Percutaneous Coronary Intervention in Optimally Treated Stable Coronary Patients
Background—The COURAGE (Clinical Outcomes Utilizing Revascularization and Aggressive druG Evaluations) trial compared the effect of percutaneous coronary intervention (PCI) plus optimal medicalExpand
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