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Stress-induced immune dysfunction: implications for health
TLDR
PNI researchers have used animal and human models to learn how the immune system communicates bidirectionally with the central nervous and endocrine systems and how these interactions impact on health. Expand
Chronic stress and age-related increases in the proinflammatory cytokine IL-6
TLDR
Evidence is provided of a key mechanism through which chronic stressors may accelerate risk of a host of age-related diseases by prematurely aging the immune response. Expand
Hostile marital interactions, proinflammatory cytokine production, and wound healing.
TLDR
These data provide further mechanistic evidence of the sensitivity of wound healing to everyday stressors and provide a window on the pathways through which hostile or abrasive relationships affect physiological functioning and health. Expand
How stress influences the immune response.
TLDR
There is now good evidence (in animal and human studies) that the magnitude of stress-associated immune dysregulation is large enough to have health implications. Expand
Spousal caregivers of dementia victims: longitudinal changes in immunity and health.
TLDR
Caregivers who reported lower levels of social support at intake and who were most distressed by dementia‐related behaviors showed the greatest and most uniformly negative changes in immune function at follow‐up. Expand
Disclosure of traumas and immune function: health implications for psychotherapy.
TLDR
Two measures of cellular immune-system function and health center visits suggested that confronting traumatic experiences was physically beneficial and the implications for psychotherapy as a preventive treatment for health problems are discussed. Expand
Emotions, morbidity, and mortality: new perspectives from psychoneuroimmunology.
TLDR
It is argued that distress-related immune dysregulation may be one core mechanism behind a large and diverse set of health risks associated with negative emotions, and resources such as close personal relationships that diminish negative emotions enhance health in part through their positive impact on immune and endocrine regulation. Expand
Psychoneuroimmunology: psychological influences on immune function and health.
TLDR
This review focuses on human psychoneuroimmunology studies published in the past decade and discusses the routes through which psychological factors influence immune function, how a stressor's duration may influence the changes observed, and the health consequences of psychosocially mediated immune dysregulation. Expand
Psychological, behavioral, and immune changes after a psychological intervention: a clinical trial.
TLDR
These data show a convergence of significant psychological, health behavior, and biologic effects after a psychological intervention for cancer patients. Expand
Stress hormones and immune function.
TLDR
Evidence is provided that stress increases neuroendocrine hormones, particularly glucocorticoids and catecholamines but to some extent also prolactin, growth hormone and nerve growth factor that have detrimental effects on immune function and implications for health. Expand
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