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Differential Structure‐Activity Relationships of Phosphoramidon Analogues for Inhibition of Three Metalloproteases: Endothelin‐Converting Enzyme, Neutral Endopeptidase, and Angiotensin‐Converting…
- P. Kukkola, P. Savage, A. Jeng
- Biology, ChemistryJournal of cardiovascular pharmacology
- 1995
TLDR
Dicarboxylic acid dipeptide neutral endopeptidase inhibitors.
- G. Ksander, R. Ghai, A. Trapani
- Biology, ChemistryJournal of medicinal chemistry
- 12 May 1995
The synthesis of three series of dicarboxylic acid dipeptide neutral endopeptidase 24.11 (NEP) inhibitors is described. In particular, the amino butyramide 21a exhibited potent NEP inhibitory…
Pharmacological profile of a non-peptidic dual inhibitor of neutral endopeptidase 24.11 and endothelin-converting enzyme.
- S. De Lombaert, R. Ghai, A. Jeng, A. Trapani, R. Webb
- BiologyBiochemical and biophysical research…
- 15 October 1994
TLDR
Occurrence of neutral endopeptidase activity in the cat carotid body and its significance in chemoreception
- G. Kumar, M. Runold, R. Ghai, N. Cherniack, N. Prabhakar
- BiologyBrain Research
- 28 May 1990
New alpha-thiol dipeptide dual inhibitors of angiotensin-I converting enzyme and neutral endopeptidase EC 3.4.24.11.
- C. Fink, Y. Qiao, C. Berry, Y. Sakane, R. Ghai, A. Trapani
- Biology, ChemistryJournal of medicinal chemistry
- 22 December 1995
TLDR
Disposition of thiorphan in DOCA-salt and spontaneously hypertensive rats.
- Y. Sakane, C. Berry, M. Hopkins, K. Singh, R. Ghai
- Biology, MedicineResearch communications in chemical pathology and…
- 1 August 1993
TLDR
Structure and location of the O-glycosidic carbohydrate units of human chorionic gonadotropin.
- M. Kessler, T. Mise, R. Ghai, O. P. Bahl
- Chemistry, BiologyThe Journal of biological chemistry
- 25 August 1979
Identification of protease 3.4.24.11 as the major atrial natriuretic factor degrading enzyme in the rat kidney
- J. L. Sonnenberg, Y. Sakane, R. Ghai
- Biology, ChemistryPeptides
- 29 February 1988
Biochemical and immunological characterization of a histone variant associated with spermatogenesis in the mouse.
- Y. Bhatnagar, K. McCullar, R. Faulkner, R. Ghai
- BiologyBiochimica et biophysica acta
- 4 October 1983
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