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Waterborne Viruses Associated With Hepatitis Outbreak
This article describes a case of viral contamination of the water supply at the Arapiles 62 camp, where bacterial indicators were unable to predict the virological quality of the drinking water
Astrovirus survival in drinking water.
A method based on infection of CaCo-2 cultured cell monolayers (CC) and reverse transcription-PCR (RT-PCR) was developed for the specific detection of infectious astrovirus. The procedure wasExpand
Viruses in Mussels: Public Health Implications and Depuration.
Studies were conducted in the common mussel ( Mytilus spp .) to evaluate the public health implications derived from shellfish contamination with human pathogenic enteric viruses. In bioaccumulationExpand
Expression of hepatitis C virus NS5A natural mutants in a hepatocytic cell line inhibits the antiviral effect of interferon in a PKR‐independent manner
The impact of hepatitis C virus NS5A protein mutations on interferon alfa (IFN‐α) signaling pathway, cell proliferation, and viability is an important issue that is still under debate. We haveExpand
Robustness of solvent/detergent treatment of plasma derivatives: a data collection from Plasma Protein Therapeutics Association member companies
BACKGROUND: Solvent/detergent (S/D) treatment is an established virus inactivation technology that has been applied in the manufacture of medicinal products derived from human plasma for more than 20Expand
The concentration of Ca2+ that solubilizes outer capsid proteins from rotavirus particles is dependent on the strain.
It has been previously shown that rotavirus maturation and stability of the outer capsid are calcium-dependent processes. More recently, it has been hypothesized that penetration of the cell membraneExpand
Activation of the interferon-inducible protein kinase PKR by Hepatocellular carcinoma derived-Hepatitis C virus core protein
Hepatitis C virus (HCV) is a major etiological agent of chronic liver disease and hepatocellular carcinoma (HCC). We demonstrate herewith that HCV core proteins encoded by sequences isolated from HCCExpand
Culture of human mesenchymal stem cells using a candidate pharmaceutical grade xeno-free cell culture supplement derived from industrial human plasma pools
IntroductionFetal bovine serum (FBS) is an animal product used as a medium supplement. The animal origin of FBS is a concern if cultured stem cells are to be utilized for human cell therapy.Expand
A new continuous epitope of hepatitis A virus
A new continuous epitope of hepatitis A virus (HAV) was defined in the VP3 protein. Convalescent sera recognised the synthetic peptide 3110–3121 (FWRGDLVFDFQV). The replacement of the arginine,Expand
Stability of HCV, HIV-1 and HBV nucleic acids in plasma samples under long-term storage.
The implementation of nucleic acid amplification technology (NAT) for detection of HCV, HIV-1 and HBV has undoubtedly contributed to the viral safety of blood, reducing the window period. OneExpand