• Publications
  • Influence
Heterochromatin, HP1 and methylation at lysine 9 of histone H3 in animals
Abstract. We show that methylated lysine 9 of histone H3 (Me9H3) is a marker of heterochromatin in divergent animal species. It localises to both constitutive and facultative heterochromatin andExpand
  • 268
  • 20
  • PDF
Positional cloning of the gene for X-linked retinitis pigmentosa 2
X-linked retinitis pigmentosa (XLRP) results from mutations in at least two different loci, designated RP2 and RP3, located at Xp11.3 and Xp21.1, respectively. The RP3 gene was recently isolated byExpand
  • 351
  • 9
Expression of mouse Tbx22 supports its role in palatogenesis and glossogenesis
TBX22 belongs to the T‐box family of transcription factors and was originally found in an in silico approach designed to identify new genes on the human Xq12‐q21 region. Mutations in TBX22 have beenExpand
  • 32
  • 5
The non-viability of uniparental mouse conceptuses correlates with the loss of the products of imprinted genes
Diploid parthenogenetic or androgenetic mouse conceptuses produce characteristic and opposite mutant phenotypes and are non-viable, presumably due to different contributions from the maternal andExpand
  • 54
  • 2
The expression of X-linked phosphoglycerate kinase in the early mouse embryo.
During early mouse embryogenesis, the activity of X-chromosomally linked maternal and paternal phosphoglycerate kinase (PGK-1) alleles was determined using electrophoretic separation of their geneExpand
  • 44
  • 1
H19 is imprinted in the choroid plexus and leptomeninges of the mouse foetus
It has been proposed that either the Igf-2 gene or the H19 gene--but not both--can be expressed from a given chromosome. Igf-2 is known to be biallelically expressed in the choroid plexus andExpand
  • 33
  • 1
Expression of X-linked phosphoglycerate kinase in early mouse embryos homozygous at the Xce locus.
The expression of maternally derived X-chromosomal Pgk-1 alleles was investigated in oocytes and early embryos of mice carrying different alleles (Xcea, Xcec) of the X-chromosome controlling elementExpand
  • 17
  • 1
Purification and properties of the phosphoglycerate mutase isozymes from the mouse.
The two homodimeric isozymes of phosphoglycerate mutase have been purified from murine kidney and muscle. No differences were observed in the Michaelis-Menten constant for the substrateExpand
  • 4
Assignment of phosphoglycerate mutase (PGAMA) to human chromosome 10. Regional mapping of GOT1 and PGAMA to subbands 10q26.1 (or q25.3).
Human phosphoglycerate mutase (PGAM, EC is under the control of two structural loci that code for subunits A and B. By means of gene-dosage studies, Bücher et al. (1980) have assigned theExpand
  • 23
Sequential expression of maternally inherited phosphoglycerate kinase-1 in the early mouse embryo.
Enzyme activities of X-linked phosphoglycerate kinase (PGK-1) and autosomal glucose phosphate isomerase (GPI-1) were determined in intact mouse blastocysts and isolated inner cell masses (ICMs).Expand
  • 8