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- Publications
- Influence
Internal consistency reliability of the fractionated and whole University of Pennsylvania Smell Identification Test
- R. L. Doty, R. Frye, U. Agrawal
- Psychology, Medicine
- Perception & psychophysics
- 1 September 1989
The internal consistency reliability (ICR) of the 40-item University of Pennsylvania Smell Identification Test (UPSIT) and its 10-, 20-, and 30-item fractions was explored, as well as the… Expand
Touch, sound and vision in human superior temporal sulcus
- M. Beauchamp, Nafi E. Yasar, R. Frye, T. Ro
- Psychology, Computer Science
- NeuroImage
- 1 July 2008
TLDR
Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain
Despite increasing evidence of oxidative stress in the pathophysiology of autism, most studies have not evaluated biomarkers within specific brain regions, and the functional consequences of… Expand
A review of research trends in physiological abnormalities in autism spectrum disorders: immune dysregulation, inflammation, oxidative stress, mitochondrial dysfunction and environmental toxicant…
- D. Rossignol, R. Frye
- Psychology, Medicine
- Molecular Psychiatry
- 6 December 2011
Recent studies have implicated physiological and metabolic abnormalities in autism spectrum disorders (ASD) and other psychiatric disorders, particularly immune dysregulation or inflammation,… Expand
Evidence linking oxidative stress, mitochondrial dysfunction, and inflammation in the brain of individuals with autism
- D. Rossignol, R. Frye
- Medicine
- Front. Physiol.
- 22 April 2014
Autism spectrum disorders (ASDs) are a heterogeneous group of neurodevelopmental disorders that are defined solely on the basis of behavioral observations. Therefore, ASD has traditionally been… Expand
Environmental toxicants and autism spectrum disorders: a systematic review
- D. Rossignol, S. J. Genuis, R. Frye
- Biology, Medicine
- Translational Psychiatry
- 1 February 2014
Although the involvement of genetic abnormalities in autism spectrum disorders (ASD) is well-accepted, recent studies point to an equal contribution by environmental factors, particularly… Expand
Mitochondrial Dysfunction Can Connect the Diverse Medical Symptoms Associated With Autism Spectrum Disorders
- R. Frye, D. Rossignol
- Medicine
- Pediatric Research
- 1 May 2011
Autism spectrum disorder (ASD) is a devastating neurodevelopmental disorder. Over the past decade, evidence has emerged that some children with ASD suffer from undiagnosed comorbid medical… Expand
High Rate of Recurrent De Novo Mutations in Developmental and Epileptic Encephalopathies.
- F. Hamdan, C. T. Myers, +103 authors J. Michaud
- Biology, Medicine
- American journal of human genetics
- 2 November 2017
Developmental and epileptic encephalopathy (DEE) is a group of conditions characterized by the co-occurrence of epilepsy and intellectual disability (ID), typically with developmental plateauing or… Expand
Surface area accounts for the relation of gray matter volume to reading-related skills and history of dyslexia.
- R. Frye, J. Liederman, Benjamin Malmberg, J. Mclean, D. Strickland, M. Beauchamp
- Psychology, Medicine
- Cerebral cortex
- 1 November 2010
It is unknown whether the abnormalities in brain structure and function observed in dyslexic readers are congenital or arise later in development. Analyzing the 2 components of gray matter volume… Expand
Cerebral folate receptor autoantibodies in autism spectrum disorder
- R. Frye, J. M. Sequeira, E. Quadros, S. James, D. Rossignol
- Medicine
- Molecular Psychiatry
- 10 January 2012
Cerebral folate deficiency (CFD) syndrome is a neurodevelopmental disorder typically caused by folate receptor autoantibodies (FRAs) that interfere with folate transport across the blood–brain… Expand