Induction of systemic immunologic tolerance to beta-lactoglobulin by oral administration of a whey protein hydrolysate.
- R. Fritsché, J. Pahud, S. Pecquet, A. Pfeifer
- Biology, MedicineJournal of Allergy and Clinical Immunology
- 1 August 1997
Peptides obtained by tryptic hydrolysis of bovine beta-lactoglobulin induce specific oral tolerance in mice.
- S. Pecquet, L. Bovetto, F. Maynard, R. Fritsché
- Chemistry, MedicineJournal of Allergy and Clinical Immunology
- 1 March 2000
These findings support the strategy of inducing oral tolerance in "at-risk" patients by means of tolerogenic cow's milk peptides or hydrolyzate.
Immunostimulatory potential of beta-lactoglobulin preparations: effects caused by endotoxin contamination.
- S. Brix, L. Bovetto, R. Fritsché, V. Barkholt, H. Frøkiaer
- Biology, MedicineJournal of Allergy and Clinical Immunology
- 1 December 2003
Animal models in food allergy: assessment of allergenicity and preventive activity of infant formulas.
- R. Fritsché
- Biology, MedicineToxicology Letters
- 11 April 2003
Cow's milk protein allergy and possible means for its prevention.
- B. Exl, R. Fritsché
- MedicineNutrition (Burbank, Los Angeles County, Calif.)
- 1 July 2001
Lactobacillus bulgaricus Proteinase Expressed in Lactococcus lactis Is a Powerful Carrier for Cell Wall-Associated and Secreted Bovine β-Lactoglobulin Fusion Proteins
- E. Bernasconi, J. Germond, M. Delley, R. Fritsché, B. Corthésy
- Biology, MedicineApplied and Environmental Microbiology
- 1 June 2002
Protein fusions relying on the use of PrtB gene products are adequate for concomitant cell surface display and secretion by recombinant L. lactis and thus may ensure maximal bioavailability of the eucaryotic antigen in the gut-associated lymphoid tissue.
Food products and allergy development, prevention and treatment.
- A. Zuercher, R. Fritsché, B. Corthésy, A. Mercenier
- MedicineCurrent Opinion in Biotechnology
- 1 April 2006
Determination of cow milk formula allergenicity in the rat model by in vitro mast cell triggering and in vivo IgE induction.
- R. Fritsché, M. Bonzon
- MedicineInternational Archives of Allergy and Applied…
- 1990
The allergenicity of cow milk formulas was assessed in vitro by their ability to trigger prelabelled 3H-serotonin release from normal rat mast cells sensitized passively with rat reaginic anti-cow…
IgE-Mediated Rat Mast Cell Triggering with Tryptic and Synthetic Peptides of Bovine β-Lactoglobulin
- R. Fritsché, K. Adel‐Patient, J. Wal
- BiologyInternational Archives of Allergy and Immunology
- 10 October 2005
A functional bivalent IgE epitope was identified at the C terminal end of βLG, able to trigger target mast cells in vitro and in vivo and has a sharply decreased allergenicity.
Oral Immunotherapy With Partially Hydrolyzed Wheat-Based Cereals: A Pilot Study
- R. Lauener, P. Eigenmann, S. Nutten
- MedicineClinical Medicine Insights: Pediatrics
- 7 September 2017
Preliminary evidence that partially hydrolyzed wheat-based cereals (pHC) is tolerated by a subset of wheat allergic patients is provided, to test its efficacy as a potential therapeutic option for wheat allergy patients.
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