• Publications
  • Influence
painDETECT: a new screening questionnaire to identify neuropathic components in patients with back pain
ABSTRACT Objective: Nociceptive and neuropathic components both contribute to pain. Since these components require different pain management strategies, correct pain diagnosis before and duringExpand
  • 1,306
  • 109
Efficacy of pregabalin in neuropathic pain evaluated in a 12-week, randomised, double-blind, multicentre, placebo-controlled trial of flexible- and fixed-dose regimens
&NA; Pregabalin binds with high affinity to the alpha2‐delta subunit protein of voltage‐gated calcium channels and, thereby, reduces release of excitatory neurotransmitters. This 12‐week randomised,Expand
  • 527
  • 14
  • PDF
Ziconotide for treatment of severe chronic pain
Pharmacological management of severe chronic pain is difficult to achieve with currently available analgesic drugs, and remains a large unmet therapeutic need. The synthetic peptide ziconotide hasExpand
  • 236
  • 9
  • PDF
Pregabalin for relief of neuropathic pain associated with diabetic neuropathy: A randomized, double‐blind study
Seven published, randomized, placebo‐controlled clinical trials with pregabalin have shown robust efficacy for relief of neuropathic pain from DPN and PHN. An investigation of the efficacy and safetyExpand
  • 197
  • 9
A cross-sectional cohort survey in 2100 patients with painful diabetic neuropathy and postherpetic neuralgia: Differences in demographic data and sensory symptoms
ABSTRACT Patients with neuropathic pain syndromes are heterogeneous. They present with a variety of sensory symptoms and pain qualities. The knowledge of these data and etiology‐specific differencesExpand
  • 256
  • 7
Pseudoradicular and radicular low-back pain – A disease continuum rather than different entities? Answers from quantitative sensory testing
&NA; To assess whether pseudoradicular low‐back pain may be associated with subclinical sensory deficits in the distal extremity, we applied the quantitative sensory testing protocol of the GermanExpand
  • 140
  • 7
Screening of neuropathic pain components in patients with chronic back pain associated with nerve root compression: a prospective observational pilot study (MIPORT)
ABSTRACT Objective: Chronic back pain is characterized by a combination of neuropathic and nociceptive mechanisms of pain generation. The prevalence of the neuropathic pain component is unknown.Expand
  • 126
  • 7
Peripheral neuropathic pain: a mechanism-related organizing principle based on sensory profiles
Abstract Patients with neuropathic pain are heterogeneous in etiology, pathophysiology, and clinical appearance. They exhibit a variety of pain-related sensory symptoms and signs (sensory profile).Expand
  • 215
  • 6
  • PDF
The evaluation of neuropathic components in low back pain
Chronic low back pain is highly prevalent in Western societies. Large epidemiological studies show that 20% to 35% of patients with back pain suffer from a neuropathic pain component. Presently,Expand
  • 182
  • 5
Opioids for chronic non-cancer pain
A 36 year old carpenter has a six month history of lower back pain with no specific clinical or radiological findings. As his pain has not responded to paracetamol and non-steroidal anti-inflammatoryExpand
  • 91
  • 5