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Role of rifampin for treatment of orthopedic implant-related staphylococcal infections: a randomized controlled trial. Foreign-Body Infection (FBI) Study Group.
Among patients with stable implants, short duration of infection, and initial debridement, patients able to tolerate long-term therapy with rifampin-ciprofloxacin experienced cure of the infection without removal of the implant.
Update of Clostridium difficile-associated disease due to PCR ribotype 027 in Europe.
The emerging strain is referred to as North American pulsed-field type 1 (NAP1) and PCR ribotype 027 and has caused outbreaks in England and Wales, Ireland, the Netherlands, Belgium, Luxembourg, and France, and has been detected in Austria, Scotland, Switzerland, Poland and Denmark.
Course and outcome of Staphylococcus aureus bacteraemia: a retrospective analysis of 308 episodes in a Swiss tertiary-care centre.
Mortality in patients with SAB remained high, despite effective antibiotic therapy, and patients with community-acquired SAB were twice as likely to die as patients with nosocomial SAB.
Update of Clostridium difficile infection due to PCR ribotype 027 in Europe, 2008.
Ongoing epidemiological surveillance of cases of CDI, with periodic characterisation of the strains involved, is required to detect clustering of cases in time and space and to monitor the emergence of new, highly virulent clones.
Microbiological tests to predict treatment outcome in experimental device-related infections due to Staphylococcus aureus.
Treatment success was not predicted by an antibiotic trough level exceeding the MIC at site of infection, and drug efficacy was predicted if the stationary-phase MBC was in the sensitive range, and if glass-adherent S. aureus was killed by low drug concentrations.
Clinical Implications of Mycobacterium kansasii Species Heterogeneity: Swiss National Survey
Investigation of the distribution of subtypes and the pathogenicity of M. kansasii strains isolated in Switzerland between 1991 and 1997 found that subtypes may improve clinical management by distinguishing pathogenic from nonpathogenic subtypes.
Low occurrence of Clostridium difficile in fecal samples of healthy calves and pigs at slaughter and in minced meat in Switzerland.
Low occurrence of C. difficile in farm animals at slaughter and in ground meat products at the retail level in Switzerland is postulated, however, further studies are necessary to confirm these preliminary data and to assess future trends.
Prevalence of Leptospira spp. in various species of small mammals caught in an inner-city area in Switzerland
In order to establish the leptospira carrier rate of small animals in an urban environment, small rodents and shrews were captured in the city of Zurich, Switzerland. Kidney specimens of 190 animals
High colonization rates of extended-spectrum β-lactamase (ESBL)-producing Escherichia coliin Swiss Travellers to South Asia– a prospective observational multicentre cohort study looking at
High colonization rates with ESBL-producing Enterobacteriaceae were found in travellers returning from South Asia, and a more common source, i.e. environmental, appears to better explain the high colonization rates.
Throat swabs are necessary to reliably detect carriers of Staphylococcus aureus.
The anterior nares are the most important screening site of colonization with Staphylococcus aureus and screening of throat swabs significantly increases the sensitivity of detection among carriers by 25.7%.