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Statistical parametric maps in functional imaging: A general linear approach
Statistical parametric maps are spatially extended statistical processes that are used to test hypotheses about regionally specific effects in neuroimaging data. The most established sorts ofExpand
Spatial registration and normalization of images
A general technique that facilitates nonlinear spatial (stereotactic) normalization and image realignment is presented that minimizes the sum of squares between two images following non linear spatial deformations and transformations of the voxel (intensity) values. Expand
A voxel-based morphometric study of ageing in 465 normal adult human brains
Voxel-based-morphometry (VBM) is a whole-brain, unbiased technique for characterizing regional cerebral volume and tissue concentration differences in structural magnetic resonance images. WeExpand
A Voxel-Based Morphometric Study of Ageing in 465 Normal Adult Human Brains
Global grey matter volume decreased linearly with age, with a significantly steeper decline in males, and local areas of accelerated loss were observed bilaterally in the insula, superior parietal gyri, central sulci, and cingulate sulci. Expand
The neural correlates of the verbal component of working memory
Comparisons of distribution of cerebral blood flow in these conditions localized the phonological store to the left supramarginal gyrus whereas the subvocal rehearsal system was associated with Broca's area, the first demonstration of the normal anatomy of the components of the 'articulatory loop'. Expand
Cerebral Asymmetry and the Effects of Sex and Handedness on Brain Structure: A Voxel-Based Morphometric Analysis of 465 Normal Adult Human Brains
There was a significant main effect of sex on brain morphology, even after accounting for the larger global volumes of grey and white matter in males. Expand
Navigation-related structural change in the hippocampi of taxi drivers.
Structural MRIs of the brains of humans with extensive navigation experience, licensed London taxi drivers, were analyzed and compared with those of control subjects who did not drive taxis, finding a capacity for local plastic change in the structure of the healthy adult human brain in response to environmental demands. Expand
Automatic classification of MR scans in Alzheimer's disease.
Assessment of support vector machines assigned individual diagnoses and whether data-sets combined from multiple scanners and different centres could be used to obtain effective classification of scans suggests an important role for computer based diagnostic image analysis for clinical practice. Expand
Area V5 of the human brain: evidence from a combined study using positron emission tomography and magnetic resonance imaging.
P positron emission tomography was used to determine the foci of relative cerebral blood flow increases produced when subjects viewed a moving checkerboard pattern, compared to viewing the same pattern when it was stationary. Expand
The anatomy of phonological and semantic processing in normal subjects.
Brain activation was assessed in the temporal, parietal and frontal multi-modal association areas that constitute parts of a large network that represent the specific anatomic substrate of the lexico-semantic processing of language. Expand