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Changes in force and calcium sensitivity in the developing avian heart.
TLDR
In skinned trabeculae, the calcium sensitivity of the contractile apparatus was higher in the embryo than in the young adult, and age-dependent changes in calcium sensitivity are correlated with isoform switching in troponin T. Expand
The relationship between calcium and the metabolism of plasma membrane phospholipids in hemolysis induced by brown spider venom phospholipase‐D toxin
TLDR
The data provided herein, suggest that the brown spider venom phospholipase‐D‐induced hemolysis of human erythrocytes is dependent on the metabolism of membrane phospholIPids, such as SM and LPC, generating bioactive products that stimulate a calcium influx into red blood cells mediated by the L‐type channel. Expand
The effect of myosin regulatory light chain phosphorylation on the frequency-dependent regulation of cardiac function.
TLDR
The data demonstrate that in cardiac muscle RLC phosphorylation is not an essential determinant of force- and pressure-frequency relations but the absence of RLCosphorylation decreases contractility in force/pressure developing preparations. Expand
Influence of ionic strength on contractile force and energy consumption of skinned fibers from mammalian and crustacean striated muscle.
TLDR
The data indicate that, even in the best of salts, destabilization of the actomyosin complex may play a role in the effect of high ionic strength on the contractile process. Expand
Effect of cardiac neural crest ablation on contractile force and calcium uptake and release in chick heart.
TLDR
Cardiac neural crest ablation in the chick embryo at stages 8-10 results in reduced contractility of the heart that can be observed as early as stage 14, and effects on Ca2+ metabolism explain, in part, the decrease in the intracellular Ca 2+ transient and myocardial contractility observed with CNCA. Expand
Mechanisms involved in the in vitro contractile dysfunction induced by different concentrations of ferrous iron in the rat myocardium.
TLDR
Iron overload can acutely impair myocardial contractility by reducing myosin-ATPase activity and myofibrillar Ca(2+) sensitivity, mediated by local production of OH and H2O2. Expand
Contraction of developing avian heart muscle.
TLDR
Developmental changes in contraction of chick heart show strong similarities with those of the mammalian myocardium, and maximal twitch force of intact trabeculae at 10-20 mM extracellular [Ca2+] is similar to maximal Ca(2+)-activated force of the trabECulae after skinning. Expand
The effect of 2,3-butanedione 2-monoxime (BDM) on ventricular trabeculae from the avian heart
TLDR
2,3-butanedione 2-monoxime (BDM, 3–30 mm) decreased twitch force of intact ventricular trabeculae isolated from 19-day embryonic chick hearts in a dose-dependent manner and was ascribed predominantly to depression of the contractile apparatus while, at higher concentrations of BDM, there is an additional inhibitory effect of B DM on excitation-contraction coupling. Expand
Anti-fatigue activity of an arabinan-rich pectin from acerola (Malpighia emarginata).
TLDR
This study provides strong evidence that M. emarginata pectic polysaccharide supplementation has anti-fatigue activity, can modify the kinetics of energy substrates (carbohydrate and fat) mobilization and the respiratory capacity of the skeletal muscle, as well the antioxidant status in the hippocampus of ACWS treated animals. Expand
Reference curves for assessing the physical growth of male Wistar rats
TLDR
The results suggest that scientists from different areas can use such references, in order to extrapolate somatic growth phases of the laboratory rat and the human model is a non-invasive alternative to assess growth and nutritional status. Expand
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