R. Ferris

Publications47
h-index23
Citations2,582
Highly Influential Citations59
Claim Author Page
Author pages are created from data sourced from our academic publisher partnerships and public sources.

Recommended Authors

  • S. Snyder
  • 1,373 Publications, 195,116 Citations
  • B. Cooper
  • 117 Publications, 5,149 Citations
  • R. A. Maxwell
  • 70 Publications, 2,028 Citations
  • J. Howard
  • 127 Publications, 3,276 Citations
  • Publications
  • Influence
Bupropion: a review of its mechanism of antidepressant activity.
BACKGROUND The mechanism of action of the novel antidepressant bupropion remains unclear after many years of study. A review of the relevant biochemical, in vivo brain microdialysis,… Expand
  • 688
  • 26
Evidence that the Acute Behavioral and Electrophysiological Effects of Bupropion (Wellbutrin®) Are Mediated by a Noradrenergic Mechanism
Bupropion (BW 323U66) has been considered a dopaminergic antidepressant based on its ability to inhibit the uptake of dopamine (DA) somewhat more selectively than it inhibits uptake of norepinephrine… Expand
  • 189
  • 9
Pharmacology of the enantiomers of threo-methylphenidate.
The pharmacology of the enantiomers of threo-methylphenidate (MPH) was evaluated in the rat to assess the relative contribution of each isomer to central and peripheral actions of the racemic drug.… Expand
  • 184
  • 4
Synthesis and evaluation of the antidepressant activity of the enantiomers of bupropion.
The synthesis of the enantiomers of bupropion, (rac)-2-tert-butylamino-3'-chloropropiophenone 1 (Wellbutrin) is described. The enantiomers were compared with the racemate in both the… Expand
  • 35
  • 4
A comparison of the capacities of isomers of amphetamine, deoxypipradrol and methylphenidate to inhibit the uptake of tritiated catecholamines into rat cerebral cortex slices, synaptosomal…
The uptake of tritiated catecholamines into crude synaptosomal preparations of rat cere bral cortex, hypothalamus and striatum, into rat cerebral cortex slices and into adrenergic nerves of rabbit… Expand
  • 301
  • 3
Studies of bupropion's mechanism of antidepressant activity.
The data obtained in these studies show that the antidepressant activity of bupropion cannot be explained by its ability to inhibit MAO present in brain or to increase the release of biogenic amines… Expand
  • 115
  • 3
Bupropion hydrochloride ((±) α‐t‐butylamino‐3‐chloropropiophenone HCl): a novel antidepressant agent
Tricyclic compounds such as amitriptyline and related substances are considered to be clinically effective antidepressant agents (Kuhn, 1958; Hollister, 1972) with a mode of action dependent on the… Expand
  • 93
  • 2
Antagonism of the enhanced susceptibility to audiogenic seizures during alcohol withdrawal in the rat by gamma-aminobutyric acid (GABA) and "GABA-mimetic" agents.
  • 96
  • 2
Total and Free Cholesterol
  • 41
  • 1
Bupropion: A new antidepressant drug, the mechanism of action of which is not associated with down-regulation of postsynaptic β-adrenergic, serotonergic (5-HT2), α2-adrenergic, imipramine and…
The present experiments were undertaken to determine: (1) whether bupropion had any direct effects on receptors present in rat brain; (2) whether the drug could down-regulate postsynaptic… Expand
  • 78
  • 1