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A controlled trial of rasagiline in early Parkinson disease: the TEMPO Study.
TLDR
Rasagiline is effective as monotherapy for patients with early PD and the 2 dosages in this trial were both effective relative to placebo.
Construction
1The Center to Protect Workers’ Rights, Silver Spring, Md. 2University of North Carolina— Chapel Hill, Chapel Hill, N.C. M anganese toxicity is initially characterized by behavior changes, fatigue,
The genetic defect causing familial Alzheimer's disease maps on chromosome 21.
TLDR
The chromosomal location of this defective gene has been discovered by using genetic linkage to DNA markers on chromosome 21 and provides an explanation for the occurrence of Alzheimer's disease-like pathology in Down syndrome.
AMERICAN ACADEMY OF NEUROLOGY
TLDR
During residency training, the resident should become familiar with the anatomy and physiology of the neuroendocrine regulatory and feedback systems and principles of hormonal treatment of neuropsychiatric disorders.
Identification of Major Outer Surface Proteins of Streptococcus agalactiae
TLDR
These studies demonstrate the successful application of proteomics as a technique for identifying vaccine candidates in a neonatal-animal model system and demonstrate that some of these sera are protective against lethal doses of bacteria.
Environmental, medical, and family history risk factors for Parkinson's disease: a New England-based case control study.
TLDR
Findings support the role of both environmental and genetic factors in the etiology in PD, and are consistent with a multifactorial model.
The `subcortical dementia' of progressive supranuclear palsy
TLDR
It is proposed as a tentative hypothesis that there may be common pathophysiological mechanisms underlying the subcortical dementias—in particular, disturbances of timing and activation.
Abnormalities in color vision and contrast sensitivity in Parkinson's disease
TLDR
The significant error in chromatic discrimination observed in Parkinson's disease patients may be due to altered intraretinal dopaminergic synaptic activity in these patients.
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