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Industrial production of β-lactam antibiotics
  • R. Elander
  • Biology
  • Applied Microbiology and Biotechnology
  • 3 April 2003
The industrial production of β-lactam antibiotics by fermentation over the past 50 years is one of the outstanding examples of biotechnology. Today, the β-lactam antibiotics, particularly penicillinsExpand
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Industrial production of beta-lactam antibiotics.
  • R. Elander
  • Medicine
  • Applied microbiology and biotechnology
  • 2003
The industrial production of beta-lactam antibiotics by fermentation over the past 50 years is one of the outstanding examples of biotechnology. Today, the beta-lactam antibiotics, particularlyExpand
  • 131
  • 6
Handbook of applied mycology
  • 310
  • 2
The β-lactam antibiotics: past, present, and future
The discovery and development of the β-lactam antibiotics are among the most powerful and successful achievements of modern science and technology. Since Fleming's accidental discovery of theExpand
  • 202
  • 2
Metabolism of tryptophan by Pseudomonas aureofaciens. 3. Production of substituted pyrrolnitrins from tryptophan analogues.
Exogenous tryptophan is metabolized by Pseudomonas aureofaciens to yield pyrrolnitrin [3-chloro-4-(2'-nitro-3'-chlorophenyl)-pyrrole], an antifungal agent. The ability of this culture to metabolizeExpand
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  • PDF
Preparation of substituted phenyl pyrroles through the metabolism of tryptophan analogues.
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Metabolism of tryptophans by Pseudomonas aureofaciens. VI. Production of pyrrolnitrin by selected Pseudomonas species.
Twenty-nine strains of Pseudomonas, classified as P. fluorescens biotype D or E or as P. multivorans, were examined for the production of pyrrolnitrin, an antifungal agent synthesized in P.Expand
  • 83
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Penicillin production by glucose-derepressed mutants ofPenicillium chrysogenum
SummaryWild-type strains ofPenicillium chrysogenum produce lower penicillin V titers in media containing excess glucose. Two mutant strains were isolated and shown to produce normal penicillin VExpand
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Strain Improvement and Preservation of β -Lactam-Producing Microorganisms
The initial discovery of Fleming’s contaminating Penicillium fungus and its remarkable antibacterial properties now date back more than 50 years. Although the Oxford group proposed in 1943 thatExpand
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  • 1