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Identification of context-specific gene regulatory networks with GEMULA - gene expression modeling using LAsso
TLDR
The proposed GEMULA is a novel approach based on linear models to predict TF-gene expression associations and TF-TF interactions from experimental data that confirms existing knowledge on gene regulatory interactions underlying neuronal outgrowth, but also generates new insights into the temporal dynamics of this gene regulatory network.
Granularin, a novel molluscan opsonin comprising a single vWF type C domain is up‐regulated during parasitation
TLDR
The data indicate that granularin represents a novel protein that acts as an opsonin in the molluscan internal defense response and stimulates phagocytosis of foreign particles by blood hemocytes.
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