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The medial temporal lobe.
The medial temporal lobe includes a system of anatomically related structures that are essential for declarative memory (conscious memory for facts and events). The system consists of the hippocampalExpand
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Recognition memory and the medial temporal lobe: a new perspective
Recognition memory is widely viewed as consisting of two components, recollection and familiarity, which have been proposed to be dependent on the hippocampus and the adjacent perirhinal cortex,Expand
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Impaired Recognition Memory in Rats after Damage to the Hippocampus
Rats with radio-frequency or ibotenic acid lesions of the hippocampus and rats with radio-frequency lesions of the fornix were tested on the visual paired comparison task (VPC), a test of recognitionExpand
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Classical conditioning and brain systems: the role of awareness.
Classical conditioning of the eye-blink response, perhaps the best studied example of associative learning in vertebrates, is relatively automatic and reflexive, and with the standard procedureExpand
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Hippocampectomy impairs the memory of recently, but not remotely, acquired trace eyeblink conditioned responses.
New Zealand male rabbits (Oryctolagus cuniculus) were trained on a trace eyeblink conditioning paradigm using a 250-ms tone conditioned stimulus, a 100-ms airpuff unconditioned stimulus, and a 500-msExpand
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Impaired Recognition Memory in Monkeys after Damage Limited to the Hippocampal Region
Monkeys with lesions limited to the hippocampal region (the hippocampus proper, the dentate gyrus, and the subiculum) were impaired on two tasks of recognition memory: delayed nonmatching to sampleExpand
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Spatial memory, recognition memory, and the hippocampus.
There is wide agreement that spatial memory is dependent on the integrity of the hippocampus, but the importance of the hippocampus for nonspatial tasks, including tasks of object recognition memoryExpand
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Dissociation between the effects of damage to perirhinal cortex and area TE.
Perirhinal cortex and area TE are immediately adjacent to each other in the temporal lobe and reciprocally interconnected. These areas are thought to lie at the interface between visual perceptionExpand
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Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats.
New granule cells are born throughout life in the dentate gyrus of the hippocampal formation. Given the fundamental role of the hippocampus in processes underlying certain forms of learning andExpand
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Medial entorhinal cortex lesions only partially disrupt hippocampal place cells and hippocampus-dependent place memory.
The entorhinal cortex provides the primary cortical projections to the hippocampus, a brain structure critical for memory. However, it remains unclear how the precise firing patterns of medialExpand
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