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Pollen Preservation and Archaeology in Eastern North America
The recovery of pollen from archaeological sites in Eastern North America has not been as successful as it has been in the western part of the continent. The depositional environment of eastern… Expand
Protection of cardiomyocytes by pinacidil during metabolic inhibition and hyperkalemia.
The objective of this study is to understand the mechanism underlying the cardioprotective effects of pinacidil, an ATP-sensitive K+ channel (K(ATP)) opener. We examined the effects of 10 microM… Expand
Effects of the calcium antagonist verapamil on in vitro synthesis of skeletal collagen and noncollagen protein.
Effects of the calcium antagonist verapamil on the synthesis of fetal rat bone collagen and noncollagen protein were investigated in tissue culture. Protein synthesis was quantitated by measuring the… Expand
Phosphorylation of brain muscarinic receptor: evidence of receptor regulation.
- A. Ho, Q. Ling, R. Duffield, P. H. Lam, J. Wang
- Chemistry, Medicine
- Biochemical and biophysical research…
- 13 February 1987
Muscarinic receptor, from porcine synaptic membrane, was purified by affinity chromatography. Molecular weight analysis by SDS-gel electrophoresis revealed one major peptide with an apparent Mr of 68… Expand
Effects of diphenylhydantoin on synthesis of collagen and noncollagen protein in tissue culture.
The direct effects of the anticonvulsant diphenylhydantoin (DPH) on collagen synthesis were examined in tissue cultures of 21-day-old fetal rat calvaria. Bones were incubated for 24 or 72 h and… Expand
Evidence for the simultaneous translocation of muscarinic acetylcholine receptor and G protein by carbachol.
Interactions between guanine nucleotide regulatory proteins (G proteins) and muscarinic acetylcholine receptors (mAChRs) were studied in vivo following carbachol treatment. Rat brain homogenates were… Expand
Effects of Ca2+ channel blockers on Ca2+ loading induced by metabolic inhibition and hyperkalemia in cardiomyocytes.
The effects of the L-type (nifedipine and verapamil) and the T-type (mibefradil) Ca2+ channel blockers on the increase in intracellular Ca2+ concentration ([Ca2+]i) induced by NaCN metabolic… Expand
Calmodulin regulation of the cholinergic receptor in the rat heart during ontogeny and senescence
The contents of calmodulin and cholinergic muscarinic receptor binding sites in the hearts of fetal, adult and aged rats have been examined. A biphasic pattern of calmodulin development was observed.… Expand
Phosphorylation-dephosphorylation of muscarinic acetylcholine receptors: evidence for the in vivo and in vitro release of receptors from rat brain plasma membrane.
The effects of phosphorylation on muscarinic acetylcholine receptors (mAChRs) were studied in vitro and in vivo using rat brain plasma membrane and receptors partially purified at least 2500-fold.… Expand
6-Hydroxydopamine-induced developmental cardiac alterations in morphology, calmodulin content, and K(2+)-mediated [Ca(2+)](i)Transient of chicken cardiomyocytes.
Calcium and the calcium-calmodulin-mediated processes have been implicated in cardiac hypertrophy. The purpose of this study was to investigate whether there is a potential role played by the… Expand