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The role of anesthesia in surgical mortality.
The role of anesthesia in contributing to surgical mortality has been studied in 33,224 patients given either spinal anesthesia or a general anesthetic to which muscle relaxants were added, and when deaths were related to the use of muscle relaxant, errors of omission or commission were always apparent. Expand
Long-term follow-up of patients who received 10,098 spinal anesthetics; syndrome of decreased intracranial pressure (headache and ocular and auditory difficulties).
The data on duration and time of onset of the headache, on the effects of postural changes, and on the visual and auditory phenomena indicate that this syndrome results from a decrease in cerebrospinal fluid pressure and that the decrease is caused by leakage of the fluid. Expand
CEREBRAL CIRCULATION AND METABOLISM DURING THIOPENTAL ANESTHESIA AND HYPERVENTILATION IN MAN
Exacerbation of pre-existing neurologic disease after spinal anesthesia.
A long-term study of spinal anesthetics followed for six months to five years found that there was no case of severe progressive neurologic disease and the major share of the lesser sequelae were related to lumbar puncture and are largely preventable by a careful technic. Expand
OXYGEN TOXICITY: THE EFFECT OF INHALATION OF HIGH CONCENTRATIONS OF OXYGEN FOR TWENTY-FOUR HOURS ON NORMAL MEN AT SEA LEVEL AND AT A SIMULATED ALTITUDE OF 18,000 FEET
It is believed that healthy men between the ages of 20 and 40 are unable to breathe 99 per cent oxygen for periods in excess of seven hours because of nausea, dyspnea and substernal soreness. Expand
Long-term follow-up of patients who received 10,098 spinal anesthetics: failure to discover major neurological sequelae.
Spinal anesthesia, an anesthetic technique with great advantages for the patient, surgeon, and anesthetist, is relatively free from the criticism of toxicity and the mortality associated with general anesthesia; on the other hand, the great hazard of spinal anesthesia in the minds of patients and surgeons is considered. Expand
REFLEX CIRCULATORY RESPONSES TO DIRECT LARYNGOSCOPY AND TRACHEAL INTUBATION PERFORMED DURING GENERAL ANESTHESIA
The respiratory and circulatory response of normal man to inhalation of 7.6 and 10.4 per cent CO2 with a comparison of the maximal ventilation produced by severe muscular exercise, inhalation of CO2…
The maximal respiratory minute volume produced by inhalation of 7.6 per cent and 10.4 per cent CO2 was compared with that resulting from exhausting muscular exercise and maximal voluntary hyperventilation and the response of a large group of normal subjects to these higher concentrations of carbon dioxide was measured. Expand
The effect of the inhalation of high and low oxygen concentrations on respiration, pulse rate, ballistocardiogram and arterial oxygen saturation (oximeter) of normal individuals.